Literature DB >> 1654242

Role of estrogens and epidermal growth factor in hepatocellular carcinoma (HCC).

A Francavilla1, C Panella, A Amoruso, A Giangaspero, L Gennari, V Mazzaferro, G Colella, D H Van Thiel, T E Starzl.   

Abstract

Estrogen (E) and epidermal growth factors (EGF) receptors were assayed in the liver of nine patients with hepatocellular carcinoma (HCC). Total E and nuclear E receptors were decreased significantly in neoplastic tissue as compared to the levels found in surrounding nonneoplastic tissue. The EGF receptor was decreased also in neoplastic tissue. On the basis of binding data, a decrease in the number but not in affinity of both the E and EGF receptors was found.

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Year:  1991        PMID： 1654242      PMCID： PMC2987624          DOI： 10.1007/bf01307526

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN： 0163-2116            Impact factor:   3.199


  24 in total

1.  The fluorometric measurement of deoxyribonucleic acid in animal tissues with special reference to the central nervous system.

Authors:  J M KISSANE; E ROBINS
Journal:  J Biol Chem       Date:  1958-07       Impact factor: 5.157

Review 2.  Regulation of liver growth: protooncogenes and transforming growth factors.

Authors:  N Fausto; J E Mead
Journal:  Lab Invest       Date:  1989-01       Impact factor: 5.662

3.  Human epidermal growth factor and the proliferation of human fibroblasts.

Authors:  G Carpenter; S Cohen
Journal:  J Cell Physiol       Date:  1976-06       Impact factor: 6.384

4.  The effect of estrogen and tamoxifen on hepatocyte proliferation in vivo and in vitro.

Authors:  A Francavilla; L Polimeno; A DiLeo; M Barone; P Ove; M Coetzee; P Eagon; L Makowka; G Ambrosino; V Mazzaferro
Journal:  Hepatology       Date:  1989-04       Impact factor: 17.425

Review 5.  Estrogenic regulation of growth and polypeptide growth factor secretion in human breast carcinoma.

Authors:  R B Dickson; M E Lippman
Journal:  Endocr Rev       Date:  1987-02       Impact factor: 19.871

6.  Estrogen-binding proteins of male rat liver: influences of hormonal changes.

Authors:  P K Eagon; S E Fisher; A F Imhoff; L E Porter; R R Stewart; D H Van Thiel; R Lester
Journal:  Arch Biochem Biophys       Date:  1980-05       Impact factor: 4.013

7.  Regenerating rat liver: correlations between estrogen receptor localization and deoxyribonucleic acid synthesis.

Authors:  A Francavilla; A di Leo; P K Eagon; S Q Wu; P Ove; D H van Thiel; T E Starzl
Journal:  Gastroenterology       Date:  1984-03       Impact factor: 22.682

8.  Immunohistochemical localization of nerve growth factor and epidermal growth factor in guinea pig prostate gland.

Authors:  H Shikata; N Utsumi; M Hiramatsu; N Minami; N Nemoto; T Shikata
Journal:  Histochemistry       Date:  1984

9.  Transforming growth factors in the urine of normal, pregnant, and tumor-bearing humans.

Authors:  D R Twardzik; S A Sherwin; J Ranchalis; G J Todaro
Journal:  J Natl Cancer Inst       Date:  1982-10       Impact factor: 13.506

10.  Different response to epidermal growth factor of hepatocytes in cultures isolated from male or female rat liver. Inhibitor effect of estrogen on binding and mitogenic effect of epidermal growth factor.

Authors:  A Francavilla; P Ove; L Polimeno; C Sciascia; M Coetzee; R Pellici; S Todo; I Kam; T E Starzl
Journal:  Gastroenterology       Date:  1987-09       Impact factor: 22.682
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  2 in total

Review 1.  Role of sex steroid receptors in pathobiology of hepatocellular carcinoma.

Authors:  Mamta Kalra; Jary Mayes; Senait Assefa; Anil-K Kaul; Rashmi Kaul
Journal:  World J Gastroenterol       Date:  2008-10-21       Impact factor: 5.742

2.  Alternative splicing of estrogen receptor alpha in hepatocellular carcinoma.

Authors:  Jian Zhang; Jianwei Ren; Jiamin Wei; Charing C N Chong; Dongjie Yang; Yulong He; George G Chen; Paul B S Lai
Journal:  BMC Cancer       Date:  2016-11-30       Impact factor: 4.430
  2 in total

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