Literature DB >> 1654171

Receptor-mediated changes in intracellular [Ca2+] in cultured rat brain capillary endothelial cells.

P A Revest1, N J Abbott, J I Gillespie.   

Abstract

Agents which are known to alter blood-brain barrier permeability have been tested for their ability to raise [Ca2+]i in rat brain capillary endothelial cells loaded with the calcium indicator Fura-2, and subjected to dual wavelength excitation. The cells show increases in [Ca2+]i in response to bradykinin, histamine and ATP. Possible sources of this calcium are discussed.

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Year:  1991        PMID: 1654171     DOI: 10.1016/0006-8993(91)90614-2

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  15 in total

Review 1.  Dynamics of CNS barriers: evolution, differentiation, and modulation.

Authors:  N Joan Abbott
Journal:  Cell Mol Neurobiol       Date:  2005-02       Impact factor: 5.046

2.  Na+-Ca2+ exchange and its implications for calcium homeostasis in primary cultured rat brain microvascular endothelial cells.

Authors:  E Dömötör; N J Abbott; V Adam-Vizi
Journal:  J Physiol       Date:  1999-02-15       Impact factor: 5.182

3.  Modulation of intracellular Ca2+ concentration in brain microvascular endothelial cells in vitro by acoustic cavitation.

Authors:  Juyoung Park; Zhenzhen Fan; Ronald E Kumon; Mohamed E H El-Sayed; Cheri X Deng
Journal:  Ultrasound Med Biol       Date:  2010-07       Impact factor: 2.998

4.  Histamine induces a selective albumin permeation through the blood-brain barrier in vitro.

Authors:  M A Deli; M P Dehouck; R Cecchelli; C S Abrahám; F Joó
Journal:  Inflamm Res       Date:  1995-04       Impact factor: 4.575

5.  The pharmacology of nucleotide receptors on primary rat brain endothelial cells grown on a biological extracellular matrix: effects on intracellular calcium concentration.

Authors:  I Sipos; E Dömötör; N J Abbott; V Adam-Vizi
Journal:  Br J Pharmacol       Date:  2000-11       Impact factor: 8.739

6.  Regulation of cerebral microvascular permeability by histamine in the anaesthetized rat.

Authors:  M H Sarker; A S Easton; P A Fraser
Journal:  J Physiol       Date:  1998-03-15       Impact factor: 5.182

Review 7.  Targeted drug delivery across the blood-brain barrier using ultrasound technique.

Authors:  Cheri X Deng
Journal:  Ther Deliv       Date:  2010-12

8.  Stimulation of phospholipase C in cultured microvascular endothelial cells from human frontal lobe by histamine, endothelin and purinoceptor agonists.

Authors:  J R Purkiss; D West; L C Wilkes; C Scott; P Yarrow; G F Wilkinson; M R Boarder
Journal:  Br J Pharmacol       Date:  1994-04       Impact factor: 8.739

9.  Characteristics of nucleotide receptors that cause elevation of cytoplasmic calcium in immortalized rat brain endothelial cells (RBE4) and in primary cultures.

Authors:  M Nobles; P A Revest; P O Couraud; N J Abbott
Journal:  Br J Pharmacol       Date:  1995-08       Impact factor: 8.739

10.  Regulation of blood-brain barrier permeability by transient receptor potential type C and type v calcium-permeable channels.

Authors:  Rachel C Brown; Ling Wu; Kali Hicks; Roger G O'neil
Journal:  Microcirculation       Date:  2008-05       Impact factor: 2.628

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