| Literature DB >> 16541204 |
Yasunobu Takizawa1, Hiroko Kanda, Kojiro Sato, Kimito Kawahata, Akihiro Yamaguchi, Hiroshi Uozaki, Jun Shimizu, Shoji Tsuji, Yoshikata Misaki, Kazuhiko Yamamoto.
Abstract
A 58-year-old man concurrently developed polymyositis (PM), interstitial lung disease, and nephrotic-range proteinuria. Renal biopsy revealed focal mesangial proliferative glomerulonephritis (mesPGN) with depositions of immunoglobulin and complements. A combination therapy of corticosteroid, intravenous immunoglobulin, and cyclosporine was found very effective for the patient. Glomerulonephritis associated with PM/dermatomyositis (DM) is rare. In our review of related literature, mesPGN was exclusively observed in polymyositis while membranous nephropathy in DM. The mechanism underlying the association between myositis and glomerulonephritis remains to be elucidated.Entities:
Mesh:
Year: 2006 PMID: 16541204 DOI: 10.1007/s10067-006-0200-y
Source DB: PubMed Journal: Clin Rheumatol ISSN: 0770-3198 Impact factor: 2.980