Literature DB >> 16540807

Estimates of body fat in children by Hologic QDR-2000 and QDR-4500A dual-energy X-ray absorptiometers compared with deuterium dilution.

Delphine R Robotham1, Dale A Schoeller, Arlene B Mercado, Margaret C Mirch, Kelly R Theim, James C Reynolds, Jack A Yanovski.   

Abstract

We evaluated the accuracy with which the Hologic QDR-4500A and QDR-2000 densitometers measure fat mass (FM) in 95 children. FM was derived from total body water measured by deuterium dilution (DD) in all children, by QDR-4500A in 50, and by QDR-2000 in 45 children. Compared with DD, both instruments underestimated FM (QDR-4500A: 3.35 +/- 2.5 kg, P < 0.0001; QDR-2000: 1.05 +/- 1.5 kg, P < 0.0001). Both absorptiometers showed magnitude biases relative to DD (QDR-4500: r = +0.70, P < 0.001; QDR-2000: r = -0.51, P < 0.001). We conclude that neither densitometer is equivalent to DD for estimation of children's FM. The QDR-4500A's current calibration seems to provide an even greater underestimate of FM than the QDR-2000.

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Year:  2006        PMID: 16540807      PMCID: PMC1861847          DOI: 10.1097/01.mpg.0000189373.31697.15

Source DB:  PubMed          Journal:  J Pediatr Gastroenterol Nutr        ISSN: 0277-2116            Impact factor:   2.839


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