Literature DB >> 1654076

Prognostic value of serum thymidine kinase, tissue polypeptide antigen and neuron specific enolase in patients with small cell lung cancer.

A van der Gaast1, W L van Putten, R Oosterom, M Cozijnsen, R Hoekstra, T A Splinter.   

Abstract

In a group of seventy patients with small cell lung cancer the prognostic value of serum tumour markers was determined. Thymidine kinase (TK), tissue polypeptide antigen (TPA) and lactate dehydrogenase (LDH) but not neuron specific enolase (NSE) correlated significantly with survival. Since all markers were strongly interrelated with each other and with the extent of disease, the combined determination of TK, TPA and LDH or the combination of disease extent and a marker yielded no more prognostic information than a single measurement of one of these variables.

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Year:  1991        PMID： 1654076      PMCID： PMC1977505          DOI： 10.1038/bjc.1991.309

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  13 in total

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2.  Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients.

Authors:  T Cerny; V Blair; H Anderson; V Bramwell; N Thatcher
Journal:  Int J Cancer       Date:  1987-02-15       Impact factor: 7.396

3.  Serum neuron-specific enolase. A marker for disease extent and response to therapy for small-cell lung cancer.

Authors:  G M Akoun; H M Scarna; B J Milleron; M P Bénichou; D P Herman
Journal:  Chest       Date:  1985-01       Impact factor: 9.410

4.  Prognostic significance of laboratory parameters measured at diagnosis in small cell carcinoma of the lung.

Authors:  R L Souhami; I Bradbury; D M Geddes; S G Spiro; P G Harper; J S Tobias
Journal:  Cancer Res       Date:  1985-06       Impact factor: 12.701

5.  Serum deoxythymidine kinase in small cell carcinoma of the lung. Relation to clinical features, prognosis, and other biochemical markers.

Authors:  J S Gronowitz; L Steinholtz; C F Källander; H Hagberg; J Bergh
Journal:  Cancer       Date:  1986-07-01       Impact factor: 6.860

6.  Tumor markers in bronchogenic carcinoma. Superiority of tissue polypeptide antigen to carcinoembryonic antigen and carbohydrate antigenic determinant 19-9.

Authors:  G F Buccheri; D Ferrigno; A M Sartoris; B Violante; F Vola; A Curcio
Journal:  Cancer       Date:  1987-07-01       Impact factor: 6.860

7.  Prognostic factors in small cell carcinoma of the lung: a cancer and leukemia group B study.

Authors:  L H Maurer; T F Pajak
Journal:  Cancer Treat Rep       Date:  1981 Sep-Oct

8.  Neuron specific enolase expression in carcinoma of the lung.

Authors:  J G Reeve; J Stewart; J V Watson; D Wulfrank; P R Twentyman; N M Bleehen
Journal:  Br J Cancer       Date:  1986-04       Impact factor: 7.640

9.  The prognostic influence of serum neuron specific enolase in small cell lung cancer.

Authors:  L G Jørgensen; K Osterlind; H H Hansen; E H Cooper
Journal:  Br J Cancer       Date:  1988-12       Impact factor: 7.640

10.  Evaluation of a radioimmunoassay for neuron specific enolase in small cell lung cancer.

Authors:  E H Cooper; T A Splinter; D A Brown; M F Muers; M D Peake; S L Pearson
Journal:  Br J Cancer       Date:  1985-09       Impact factor: 7.640
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  5 in total

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3.  Distinction of two different classes of small-cell lung cancer cell lines by enzymatically inactive neuron-specific enolase.

Authors:  T A Splinter; C F Verkoelen; M Vlastuin; T C Kok; G Rijksen; K G Haglid; F Boomsma; A van de Gaast
Journal:  Br J Cancer       Date:  1992-12       Impact factor: 7.640

4.  Deoxythymidine kinase in the tumour cells and serum of patients with non-Hodgkin lymphomas.

Authors:  S Rehn; J S Gronowitz; C Källander; C Sundström; B Glimelius
Journal:  Br J Cancer       Date:  1995-05       Impact factor: 7.640

5.  Thymidine Kinase Type 1 and C-Reactive Protein Concentrations in Dogs with Spontaneously Occurring Cancer.

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  5 in total

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