Literature DB >> 16537885

Glucose-insulin and potassium infusions in septic shock.

Shahir S Hamdulay1, Ali Al-Khafaji, Hugh Montgomery.   

Abstract

Glucose-insulin and potassium (GIK) infusions are beneficial in treating ischemic myocardial depression. Myocardial depression is also an important feature in septic shock. We describe two cases of pressor-resistant hypodynamic septic shock that responded to high-dose GIK infusions. In each case, hemodynamic profiles improved sufficiently to allow withdrawal of vasopressor agents. Further assessment of GIK in patients with hypodynamic septic shock is necessary to confirm efficacy and prognostic significance.

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Year:  2006        PMID： 16537885     DOI： 10.1378/chest.129.3.800

Source DB:  PubMed          Journal:  Chest        ISSN： 0012-3692            Impact factor:   9.410


  8 in total

1.  Glucose-insulin-potassium correlates with hemodynamic improvement in patients with septic myocardial dysfunction.

Authors:  Won-Young Kim; Moon Seong Baek; Young Shin Kim; Jarim Seo; Jin Won Huh; Chae-Man Lim; Younsuck Koh; Sang-Bum Hong
Journal:  J Thorac Dis       Date:  2016-12       Impact factor: 2.895

2.  Intensive Care Foundation Research Free Paper Presentations.

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Journal:  J Intensive Care Soc       Date:  2015-03-17

Review 3.  Catecholamines for inflammatory shock: a Jekyll-and-Hyde conundrum.

Authors:  Davide Tommaso Andreis; Mervyn Singer
Journal:  Intensive Care Med       Date:  2016-02-12       Impact factor: 17.440

4.  Use of insulin to decrease septic shock-induced myocardial depression in a porcine model.

Authors:  Yosef Levenbrown; Scott Penfil; Elena Rodriguez; Yan Zhu; Jobayer Hossain; A Majeed Bhat; Anne Hesek; Karen B O'Neil; Kelly Tobin; Thomas H Shaffer
Journal:  Inflammation       Date:  2013-12       Impact factor: 4.092

Review 5.  The role of protein O-linked beta-N-acetylglucosamine in mediating cardiac stress responses.

Authors:  John C Chatham; Richard B Marchase
Journal:  Biochim Biophys Acta       Date:  2009-07-14

6.  Insulin-dependent rescue from cardiogenic shock is not mediated by phospholamban phosphorylation.

Authors:  Naa-Adjeley Ablorh; Florentin Nitu; Kristin Engebretsen; David D Thomas; Joel S Holger
Journal:  Clin Toxicol (Phila)       Date:  2009-04       Impact factor: 4.467

Review 7.  Effect of glucose-insulin-potassium infusion on mortality in critical care settings: a systematic review and meta-analysis.

Authors:  Michael A Puskarich; Michael S Runyon; Stephen Trzeciak; Jeffrey A Kline; Alan E Jones
Journal:  J Clin Pharmacol       Date:  2009-05-05       Impact factor: 3.126

Review 8.  Therapeutic strategies for high-dose vasopressor-dependent shock.

Authors:  Estevão Bassi; Marcelo Park; Luciano Cesar Pontes Azevedo
Journal:  Crit Care Res Pract       Date:  2013-09-15
  8 in total

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