Literature DB >> 1653762

Mapping and direct visualization of a region-specific viral DNA integration site on chromosome 19q13-qter.

R M Kotin1, J C Menninger, D C Ward, K I Berns.   

Abstract

A human parvovirus, adeno-associated virus (AAV), is unique among eukaryotic DNA viruses in its ability to integrate site specifically into a defined region of human chromosome 19. In this study we used in situ hybridization to visualized directly the site of AAV DNA integration in latently infected human cell lines and normal human cells.

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Year:  1991        PMID： 1653762     DOI： 10.1016/0888-7543(91)90470-y

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  110 in total

1.  Adeno-associated virus type 2-mediated gene transfer: altered endocytic processing enhances transduction efficiency in murine fibroblasts.

Authors:  J Hansen; K Qing; A Srivastava
Journal:  J Virol       Date:  2001-05       Impact factor: 5.103

2.  Factors affecting the terminal resolution site endonuclease, helicase, and ATPase activities of adeno-associated virus type 2 Rep proteins.

Authors:  J Wu; M D Davis; R A Owens
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

Review 3.  Adeno-associated virus vectors and hematology.

Authors:  D W Russell; M A Kay
Journal:  Blood       Date:  1999-08-01       Impact factor: 22.113

4.  Adeno-associated virus site-specifically integrates into a muscle-specific DNA region.

Authors:  N Dutheil; F Shi; T Dupressoir; R M Linden
Journal:  Proc Natl Acad Sci U S A       Date:  2000-04-25       Impact factor: 11.205

5.  DNA sequence motifs which direct adeno-associated virus site-specific integration in a model system.

Authors:  P Meneses; K I Berns; E Winocour
Journal:  J Virol       Date:  2000-07       Impact factor: 5.103

6.  The persistence of alien genomes.

Authors:  P Tattersall
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-06       Impact factor: 11.205

7.  Mutational analysis of adeno-associated virus type 2 Rep68 protein endonuclease activity on partially single-stranded substrates.

Authors:  M D Davis; J Wu; R A Owens
Journal:  J Virol       Date:  2000-03       Impact factor: 5.103

8.  Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblasts.

Authors:  J Hansen; K Qing; H J Kwon; C Mah; A Srivastava
Journal:  J Virol       Date:  2000-01       Impact factor: 5.103

9.  High-titer, wild-type free recombinant adeno-associated virus vector production using intron-containing helper plasmids.

Authors:  L Cao; Y Liu; M J During; W Xiao
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

10.  Use of recombinant angiostatin to prevent retinal neovascularization.

Authors:  K I Berns; P Meneses; R Duvoisin; P Laipis; W Hauswirth
Journal:  Trans Am Clin Climatol Assoc       Date:  2001
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