Literature DB >> 16535249

Stereospecific Preparation of an Excitatory Amino Acid Antagonist with d-Hydantoinase from Agrobacterium tumefaciens as a Biocatalyst.

D R Durham, J E Weber.   

Abstract

Extracts of Agrobacterium tumefaciens were used to mediate the stereospecific conversion of a racemic hydantoin to a carbamyl d-amino acid derivative, which is a precursor to (2R,4R,5S)-2-amino-4,5-(1,2-cyclohexyl)-7-phosphonoheptanoic acid (ACPA). ACPA has therapeutic value as an excitatory amino acid antagonist.

Entities:  

Year:  1996        PMID： 16535249      PMCID： PMC1388787          DOI： 10.1128/aem.62.2.739-742.1996

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  7 in total

1.  Characterization of Inorganic Biocarriers That Moderate System Upsets during Fixed-Film Biotreatment Processes.

Authors:  D R Durham; L C Marshall; J G Miller; A B Chmurny
Journal:  Appl Environ Microbiol       Date:  1994-09       Impact factor: 4.792

Review 2.  Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists.

Authors:  J C Watkins; P Krogsgaard-Larsen; T Honoré
Journal:  Trends Pharmacol Sci       Date:  1990-01       Impact factor: 14.819

Review 3.  Structural, conformational, and stereochemical requirements of central excitatory amino acid receptors.

Authors:  J J Hansen; P Krogsgaard-Larsen
Journal:  Med Res Rev       Date:  1990 Jan-Mar       Impact factor: 12.944

Review 4.  The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system.

Authors:  D T Monaghan; R J Bridges; C W Cotman
Journal:  Annu Rev Pharmacol Toxicol       Date:  1989       Impact factor: 13.820

5.  Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist.

Authors:  J W Ferkany; D J Kyle; J Willets; W J Rzeszotarski; M E Guzewska; S R Ellenberger; S M Jones; A I Sacaan; L D Snell; S Borosky
Journal:  J Pharmacol Exp Ther       Date:  1989-07       Impact factor: 4.030

6.  [Histochemical localization of acetylcholinesterase in the chick ciliary ganglion during development].

Authors:  C Olivieri-Sangiacomo; A Del Fà; C Gangitano
Journal:  Boll Soc Ital Biol Sper       Date:  1981-11-15

7.  Properties of D-hydantoinase from Agrobacterium tumefaciens and its use for the preparation of N-carbamyl D-amino acids.

Authors:  D R Durham; J E Weber
Journal:  Biochem Biophys Res Commun       Date:  1995-11-22       Impact factor: 3.575
  7 in total
  1 in total

1.  Cyclic-imide-hydrolyzing activity of D-hydantoinase from Blastobacter sp. strain A17p-4.

Authors:  C L Soong; J Ogawa; M Honda; S Shimizu
Journal:  Appl Environ Microbiol       Date:  1999-04       Impact factor: 4.792
  1 in total

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