| Literature DB >> 16534115 |
S Renaud1, P Fuhr, M Gregor, K Schweikert, D Lorenz, C Daniels, G Deuschl, A Gratwohl, A J Steck.
Abstract
Rituximab has been administered successfully in patients with polyneuropathy associated with antibodies to myelin-associated glycoprotein (anti-MAG). The authors present a follow-up study with high-dose rituximab. Increase of rituximab from 375 mg/m2 to a dose of 750 mg/m2 was well tolerated and led to clinical improvement in four of eight patients, along with improvement of nerve conduction velocities and a reduction of anti-MAG antibody titers.Entities:
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Year: 2006 PMID: 16534115 DOI: 10.1212/01.wnl.0000201193.00382.b3
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910