Literature DB >> 1653211

Gyrase inhibitors increase the content of knotted DNA species of plasmid pBR322 in Escherichia coli.

S Ishii1, T Murakami, K Shishido.   

Abstract

Treatment of Escherichia coli cells harboring pBR322 with the DNA gyrase inhibitors oxolinic acid and coumermycin A1 led to an increase in the content of knotted pBR322 molecules. This phenomenon was attributed to inhibition of gyrase-catalyzed unknotting of the plasmid DNA knotted by transcription.

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Year:  1991        PMID： 1653211      PMCID： PMC208270          DOI： 10.1128/jb.173.17.5551-5553.1991

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  15 in total

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8.  A topoisomerase from Escherichia coli related to DNA gyrase.

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  13 in total

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5.  The Dynamic Interplay Between DNA Topoisomerases and DNA Topology.

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9.  Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification.

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