Literature DB >> 16531371

Blast lung injury.

Scott M Sasser1, Richard W Sattin, Richard C Hunt, Jon Krohmer.   

Abstract

Current trends in global terrorism mandate that emergency medical services, emergency medicine and other acute care clinicians have a basic understanding of the physics of explosions, the types of injuries that can result from an explosion, and current management for patients injured by explosions. High-order explosive detonations result in near instantaneous transformation of the explosive material into a highly pressurized gas, releasing energy at supersonic speeds. This results in the formation of a blast wave that travels out from the epicenter of the blast. Primary blast injuries are characterized by anatomical and physiological changes from the force generated by the blast wave impacting the body's surface, and affect primarily gas-containing structures (lungs, gastrointestinal tract, ears). "Blast lung" is a clinical diagnosis and is characterized as respiratory difficulty and hypoxia without obvious external injury to the chest. It may be complicated by pneumothoraces and air emboli and may be associated with multiple other injuries. Patients may present with a variety of symptoms, including dyspnea, chest pain, cough, and hemoptysis. Physical examination may reveal tachypnea, hypoxia, cyanosis, and decreased breath sounds. Chest radiography, computerized tomography, and arterial blood gases may assist with diagnosis and management; however, they should not delay diagnosis and emergency interventions in the patient exposed to a blast. High flow oxygen, airway management, tube thoracostomy in the setting of pneumothoraces, mechanical ventilation (when required) with permissive hypercapnia, and judicious fluid administration are essential components in the management of blast lung injury.

Entities:  

Mesh:

Year:  2006        PMID: 16531371     DOI: 10.1080/10903120500540912

Source DB:  PubMed          Journal:  Prehosp Emerg Care        ISSN: 1090-3127            Impact factor:   3.077


  11 in total

Review 1.  Primary blast injuries--an updated concise review.

Authors:  Daniel Dante Yeh; William P Schecter
Journal:  World J Surg       Date:  2012-05       Impact factor: 3.352

Review 2.  [Terrorism--a new dimension in trauma care].

Authors:  R Schwab; C Güsgen; S Hentsch; E Kollig
Journal:  Chirurg       Date:  2007-10       Impact factor: 0.955

3.  Computational Modeling of Primary Blast Lung Injury: Implications for Ventilator Management.

Authors:  Jacob Herrmann; Merryn H Tawhai; David W Kaczka
Journal:  Mil Med       Date:  2019-03-01       Impact factor: 1.437

4.  Examining lethality risk for rodent studies of primary blast lung injury.

Authors:  William Brad Hubbard; Christina Hall; Venkata Siva Sai Suijith Sajja; Erink Lavik; Pamela VandeVord
Journal:  Biomed Sci Instrum       Date:  2014

5.  The effect of aerosolized indomethacin on lung inflammation and injury in a rat model of blunt chest trauma

Authors:  Raymond L. Kao; Weixiong Huang; Claudio M. Martin; Tao Rui
Journal:  Can J Surg       Date:  2018-12-01       Impact factor: 2.089

Review 6.  [Terrorist attack trauma - an individual entity of polytrauma : A 10-year update].

Authors:  C Güsgen; A Franke; S Hentsch; E Kollig; R Schwab
Journal:  Chirurg       Date:  2017-10       Impact factor: 0.955

7.  Managing traumatic brain injury secondary to explosions.

Authors:  Paula Burgess; Ernest E Sullivent; Scott M Sasser; Marlena M Wald; Eric Ossmann; Vikas Kapil
Journal:  J Emerg Trauma Shock       Date:  2010-04

8.  Rat injury model under controlled field-relevant primary blast conditions: acute response to a wide range of peak overpressures.

Authors:  Maciej Skotak; Fang Wang; Aaron Alai; Aaron Holmberg; Seth Harris; Robert C Switzer; Namas Chandra
Journal:  J Neurotrauma       Date:  2013-06-28       Impact factor: 5.269

Review 9.  Stem cell applications in military medicine.

Authors:  Gregory T Christopherson; Leon J Nesti
Journal:  Stem Cell Res Ther       Date:  2011-10-19       Impact factor: 6.832

10.  Evaluating Primary Blast Effects In Vitro.

Authors:  Niall J Logan; Hari Arora; Claire A Higgins
Journal:  J Vis Exp       Date:  2017-09-18       Impact factor: 1.355

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