| Literature DB >> 16530483 |
Thomas Prod'homme1, Martin S Weber, Lawrence Steinman, Scott S Zamvil.
Abstract
Disturbances in crosstalk between the immune system and the sympathetic nervous system (SNS) can contribute to the pathogenesis of Th1-mediated autoimmunity. Recent studies indicate that neuropeptide Y (NPY) has a major role in the regulation of Th1 responses. The precise role of NPY has been an enigma, but a recent study provides a breakthrough, demonstrating that NPY has a bimodal role as a negative regulator of T cells and an activator of antigen-presenting cell function.Entities:
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Year: 2006 PMID： 16530483 DOI： 10.1016/j.it.2006.02.003
Source DB: PubMed Journal: Trends Immunol ISSN： 1471-4906 Impact factor: 16.687