Literature DB >> 16530241

Amino acid sequence of RTX-A's isoform actinoporin from the sea anemone, Radianthus macrodactylus.

Anna Il'ina1, Aleksey Lipkin, Ekaterina Barsova, Marina Issaeva, Elena Leychenko, Konstantin Guzev, Margarita Monastyrnaya, Sergey Lukyanov, Emma Kozlovskaya.   

Abstract

The amino acid sequence of actinoporin RTX-A (175 aa) from the sea anemone Radianthus macrodactylus was determined by sequencing of clones obtained via amplification of cDNA. It was established that RTX-A possessed high homology with HmgIII from Heteractis magnifica (87%) and StI, StII from Stichodactyla helianthus (84 and 87%, respectively). The analysis of structural and functional relationships within RTX-A was carried out. The some disagreement concerning to significant role of several amino acid residues for actinoporins exhibition of hemolytic activity was found.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16530241     DOI： 10.1016/j.toxicon.2005.12.014

Source DB:  PubMed          Journal:  Toxicon        ISSN： 0041-0101            Impact factor:   3.033


  9 in total

1.  A pore-forming toxin requires a specific residue for its activity in membranes with particular physicochemical properties.

Authors:  Koldo Morante; Jose M M Caaveiro; Koji Tanaka; Juan Manuel González-Mañas; Kouhei Tsumoto
Journal:  J Biol Chem       Date:  2015-03-10       Impact factor: 5.157

2.  The anticancer effects of actinoporin RTX-A from the sea anemone Heteractis crispa (=Radianthus macrodactylus).

Authors:  Sergey Fedorov; Sergey Dyshlovoy; Margarita Monastyrnaya; Larisa Shubina; Elena Leychenko; Emma Kozlovskaya; Jun-O Jin; Jong-Young Kwak; Ann M Bode; Zigang Dong; Valentin Stonik
Journal:  Toxicon       Date:  2009-11-26       Impact factor: 3.033

Review 3.  Sea anemone (Cnidaria, Anthozoa, Actiniaria) toxins: an overview.

Authors:  Bárbara Frazão; Vitor Vasconcelos; Agostinho Antunes
Journal:  Mar Drugs       Date:  2012-08-22       Impact factor: 6.085

4.  Hct-a is a new actinoporin family from the heteractis crispa sea anemone.

Authors:  E V Leichenko; M M Monastirnaya; E A Zelepuga; E S Tkacheva; M P Isaeva; G N Likhatskaya; S D Anastyuk; E P Kozlovskaya
Journal:  Acta Naturae       Date:  2014-10       Impact factor: 1.845

5.  Kunitz-Type Peptide HCRG21 from the Sea Anemone Heteractis crispa Is a Full Antagonist of the TRPV1 Receptor.

Authors:  Margarita Monastyrnaya; Steve Peigneur; Elena Zelepuga; Oksana Sintsova; Irina Gladkikh; Elena Leychenko; Marina Isaeva; Jan Tytgat; Emma Kozlovskaya
Journal:  Mar Drugs       Date:  2016-12-15       Impact factor: 5.118

6.  Multigene Family of Pore-Forming Toxins from Sea Anemone Heteractis crispa.

Authors:  Elena Leychenko; Marina Isaeva; Ekaterina Tkacheva; Elena Zelepuga; Aleksandra Kvetkina; Konstantin Guzev; Margarita Monastyrnaya; Emma Kozlovskaya
Journal:  Mar Drugs       Date:  2018-05-24       Impact factor: 5.118

Review 7.  A Review of Toxins from Cnidaria.

Authors:  Isabella D'Ambra; Chiara Lauritano
Journal:  Mar Drugs       Date:  2020-10-06       Impact factor: 5.118

8.  Atypical reactive center Kunitz-type inhibitor from the sea anemone Heteractis crispa.

Authors:  Irina Gladkikh; Margarita Monastyrnaya; Elena Leychenko; Elena Zelepuga; Victoria Chausova; Marina Isaeva; Stanislav Anastyuk; Yaroslav Andreev; Steve Peigneur; Jan Tytgat; Emma Kozlovkaya
Journal:  Mar Drugs       Date:  2012-07-19       Impact factor: 6.085

9.  A new multigene HCIQ subfamily from the sea anemone Heteractis crispa encodes Kunitz-peptides exhibiting neuroprotective activity against 6-hydroxydopamine.

Authors:  Aleksandra Kvetkina; Elena Leychenko; Victoria Chausova; Elena Zelepuga; Nadezhda Chernysheva; Konstantin Guzev; Evgeny Pislyagin; Ekaterina Yurchenko; Ekaterina Menchinskaya; Dmitry Aminin; Leonid Kaluzhskiy; Alexis Ivanov; Steve Peigneur; Jan Tytgat; Emma Kozlovskaya; Marina Isaeva
Journal:  Sci Rep       Date:  2020-03-06       Impact factor: 4.379
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.