| Literature DB >> 16530055 |
Ana P Cotrim1, Fumi Mineshiba, Takayuki Sugito, Yuval Samuni, Bruce J Baum.
Abstract
Salivary glands have proven to be unusual but valuable target sites for multiple clinical gene transfer applications. Access to salivary glands for gene transfer is easy. Multiple studies in animal models have yielded proofs of concept for novel treatments for damaged salivary glands following therapeutic irraditation, in Sjögren's syndrome, and for gene therapeutics systemically by way of the blood-stream and locally in the oral cavity and upper gastrointestinal tract.Entities:
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Year: 2006 PMID： 16530055 DOI： 10.1016/j.cden.2005.11.002
Source DB: PubMed Journal: Dent Clin North Am ISSN： 0011-8532