Literature DB >> 16529534

Polyhedral boron compounds as potential diagnostic and therapeutic antitumor agents.

V I Bregadze1, I B Sivaev, S A Glazun.   

Abstract

The use of polyhedral boron hydrides for cancer treatment is traditionally connected with boron neutron capture therapy. More recently, polyhedral borate anions were proposed as carriers of radionuclide label for targeted radionuclide therapy and diagnostics of cancer. Some metal derivatives of carboranes were found to demonstrate significant antitumor activity themselves. This review is designed to highlight the recent work concerning various fields of potential application of polyhedral boron compounds in anticancer diagnostics and therapy.

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Year:  2006        PMID： 16529534     DOI： 10.2174/187152006776119180

Source DB:  PubMed          Journal:  Anticancer Agents Med Chem        ISSN： 1871-5206            Impact factor:   2.505


  8 in total

1.  Synthesis and evaluation of carbaborane derivatives of indomethacin as cyclooxygenase inhibitors.

Authors:  Matthias Scholz; Anna L Blobaum; Lawrence J Marnett; Evamarie Hey-Hawkins
Journal:  Bioorg Med Chem       Date:  2011-03-27       Impact factor: 3.641

2.  Nitric oxide synthases activation and inhibition by metallacarborane-cluster-based isoform-specific affectors.

Authors:  Robert Kaplánek; Pavel Martásek; Bohumír Grüner; Satya Panda; Jakub Rak; Bettie Sue Siler Masters; Vladimír Král; Linda J Roman
Journal:  J Med Chem       Date:  2012-11-01       Impact factor: 7.446

3.  Synthesis and in vitro properties of trimethylamine- and phosphonate-substituted carboranylporphyrins for application in BNCT.

Authors:  Michael W Easson; Frank R Fronczek; Timothy J Jensen; M Graça H Vicente
Journal:  Bioorg Med Chem       Date:  2008-02-21       Impact factor: 3.641

4.  Mixed Matrix Membranes of Boron Icosahedron and Polymers of Intrinsic Microporosity (PIM-1) for Gas Separation.

Authors:  Muntazim Munir Khan; Sergey Shishatskiy; Volkan Filiz
Journal:  Membranes (Basel)       Date:  2018-01-02

5.  Pd(ii)-catalyzed synthesis of bifunctionalized carboranes via cage B-H activation of 1-CH2NH2-o-carboranes.

Authors:  Xiaolei Zhang; Hong Yan
Journal:  Chem Sci       Date:  2018-03-27       Impact factor: 9.825

6.  Homocystamide Conjugates of Human Serum Albumin as a Platform to Prepare Bimodal Multidrug Delivery Systems for Boron Neutron Capture Therapy.

Authors:  Tatyana Popova; Maya A Dymova; Ludmila S Koroleva; Olga D Zakharova; Vladimir A Lisitskiy; Valeria I Raskolupova; Tatiana Sycheva; Sergei Taskaev; Vladimir N Silnikov; Tatyana S Godovikova
Journal:  Molecules       Date:  2021-10-29       Impact factor: 4.411

7.  Synthesis of Cobalt Bis(Dicarbollide)-Curcumin Conjugates for Potential Use in Boron Neutron Capture Therapy.

Authors:  Lyubov G Dezhenkova; Anna A Druzina; Yulia L Volodina; Nadezhda V Dudarova; Natalia A Nekrasova; Olga B Zhidkova; Mikhail A Grin; Vladimir I Bregadze
Journal:  Molecules       Date:  2022-07-21       Impact factor: 4.927

Review 8.  Synthesis of Polyhedral Borane Cluster Fused Heterocycles via Transition Metal Catalyzed B-H Activation.

Authors:  Ke Cao; Cai-Yan Zhang; Tao-Tao Xu; Ji Wu; Xin-Yu Wen; Wen-Jun Jiang; Mao Chen; Junxiao Yang
Journal:  Molecules       Date:  2020-01-17       Impact factor: 4.411
  8 in total

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