Literature DB >> 16529522

Ring-opening reactions of N-methyl cyclic ketene-N,O-acetals with carboxylic acids, nitrophenol, and arylthiols.

Aihua Zhou1, Charles U Pittman.   

Abstract

Ring-opening reactions of N-methyl cyclic ketene-N,O-acetals with carboxylic acids, 4-nitrophenol, and arylthiols afforded amidoesters, amidoaryl ether, and amidothioethers, respectively, in good yields via an acid-catalyzed S(N)2 mechanism.

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Year:  2006        PMID: 16529522     DOI: 10.1021/cc050133m

Source DB:  PubMed          Journal:  J Comb Chem        ISSN: 1520-4766


  2 in total

1.  Reaction discovery using microfluidic-based multidimensional screening of polycyclic iminium ethers.

Authors:  Jennifer L Treece; John R Goodell; David Vander Velde; John A Porco; Jeffrey Aubé
Journal:  J Org Chem       Date:  2010-03-19       Impact factor: 4.354

2.  Gold(I)-catalyzed coupling reactions for the synthesis of diverse small molecules using the build/couple/pair strategy.

Authors:  Tuoping Luo; Stuart L Schreiber
Journal:  J Am Chem Soc       Date:  2009-04-22       Impact factor: 15.419

  2 in total

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