Literature DB >> 16526814

Mild organocatalytic alpha-methylenation of aldehydes.

Anniina Erkkilä1, Petri M Pihko.   

Abstract

A rapid and extremely convenient method for alpha-methylenation of aldehydes with aqueous formaldehyde is described. Two optimal catalytic systems are presented that allow short reaction times and afford the functionalized products in good to excellent yields (up to 99%) and chemoselectivity.

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Year:  2006        PMID： 16526814     DOI： 10.1021/jo052529q

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

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  5 in total

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