Literature DB >> 16525185

Whole-brain radiotherapy in the management of brain metastasis.

Deepak Khuntia1, Paul Brown, Jing Li, Minesh P Mehta.   

Abstract

Brain metastases are an important cause of morbidity and mortality, afflicting nearly 170,000 Americans annually. The prognosis for these patients is poor, with median survival times measured in months. In this review article, we present the standard treatment approach of whole-brain radiotherapy and discuss new directions, including the role of chemical modifiers and the management and prevention of neurocognitive deficits.

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Year:  2006        PMID： 16525185     DOI： 10.1200/JCO.2005.04.6185

Source DB:  PubMed          Journal:  J Clin Oncol        ISSN： 0732-183X            Impact factor:   44.544


  173 in total

1.  Chronic administration of the angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiation-induced perirhinal cortex-dependent cognitive impairment.

Authors:  Tammy C Lee; Dana Greene-Schloesser; Valerie Payne; Debra I Diz; Fang-Chi Hsu; Mitra Kooshki; Rashida Mustafa; David R Riddle; Weiling Zhao; Michael D Chan; Mike E Robbins
Journal:  Radiat Res       Date:  2012-06-12       Impact factor: 2.841

Review 2.  Renin-angiotensin system blockers and modulation of radiation-induced brain injury.

Authors:  M E Robbins; W Zhao; M A Garcia-Espinosa; D I Diz
Journal:  Curr Drug Targets       Date:  2010-11       Impact factor: 3.465

3.  Shenqi fuzheng injection attenuates irradiation-induced brain injury in mice via inhibition of the NF-κB signaling pathway and microglial activation.

Authors:  Jian Zhang; Fan Tong; Qian Cai; Ling-juan Chen; Ji-hua Dong; Gang Wu; Xiao-rong Dong
Journal:  Acta Pharmacol Sin       Date:  2015-11       Impact factor: 6.150

4.  Effective method to reduce the normal brain dose in single-isocenter hypofractionated stereotactic radiotherapy for multiple brain metastases.

Authors:  Jialu Lai; Jia Liu; Jianling Zhao; An Li; Shoupeng Liu; Zhonghua Deng; Qiaoyue Tan; Haitao Wang; Yuming Jia; Kaijian Lei; Lin Zhou
Journal:  Strahlenther Onkol       Date:  2021-03-16       Impact factor: 3.621

5.  Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice.

Authors:  Junie P Warrington; Anna Csiszar; Daniel A Johnson; Terence S Herman; Salahuddin Ahmad; Yong Woo Lee; William E Sonntag
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-12-24       Impact factor: 4.733

Review 6.  Radiation dose-volume effects in the brain.

Authors:  Yaacov Richard Lawrence; X Allen Li; Issam el Naqa; Carol A Hahn; Lawrence B Marks; Thomas E Merchant; Adam P Dicker
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-03-01       Impact factor: 7.038

7.  The breast graded prognostic assessment is associated with the survival outcomes in breast cancer patients receiving whole brain re-irradiation.

Authors:  Shih-Fan Lai; Yu-Hsuan Chen; Tony Hsiang-Kuang Liang; Che-Yu Hsu; Huang-Chun Lien; Yen-Sen Lu; Chiun-Sheng Huang; Sung-Hsin Kuo
Journal:  J Neurooncol       Date:  2018-03-20       Impact factor: 4.130

8.  Brain irradiation: effects on normal brain parenchyma and radiation injury.

Authors:  Pia C Sundgren; Yue Cao
Journal:  Neuroimaging Clin N Am       Date:  2009-11       Impact factor: 2.264

9.  PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways.

Authors:  Sriram Ramanan; Mitra Kooshki; Weiling Zhao; Fang-Chi Hsu; Mike E Robbins
Journal:  Free Radic Biol Med       Date:  2008-09-17       Impact factor: 7.376

10.  Cellular response of the rat brain to single doses of (137)Cs γ rays does not predict its response to prolonged 'biologically equivalent' fractionated doses.

Authors:  Dana M Greene-Schloesser; Mitra Kooshki; Valerie Payne; Ralph B D'Agostino; Kenneth T Wheeler; Linda J Metheny-Barlow; Mike E Robbins
Journal:  Int J Radiat Biol       Date:  2014-09       Impact factor: 2.694
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