| Literature DB >> 16524641 |
F Donelson Smith1, John D Scott.
Abstract
Intracellular signal transduction pathways require a high degree of spatial and temporal resolution in order to deliver the appropriate outputs. Specific signaling mediated by the ubiquitous second messenger cAMP and its effector, the cAMP-dependent protein kinase (PKA), is governed by the spatial organization of different pathway components by A-kinase anchoring proteins (AKAPs). This review discusses the history and future of anchored cAMP signaling pathways.Entities:
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Year: 2006 PMID: 16524641 DOI: 10.1016/j.ejcb.2006.01.011
Source DB: PubMed Journal: Eur J Cell Biol ISSN: 0171-9335 Impact factor: 4.492