Literature DB >> 1652461

Site-directed mutagenesis of La protease. A catalytically active serine residue.

V K Antonov, A E Gorbalenya, S A Kotova, T V Rotanova, E V Shimbarevich.   

Abstract

Comparative sequence analysis of Escherichia coli ATP-dependent La protease led to the suggestion that Ser679 is the catalytically active enzyme residue. Site-directed mutagenesis Ser679----Ala, investigation of the cells containing the mutant plasmid, and study of the partially purified mutant protein produced results in favour of this suggestion.

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Year:  1991        PMID： 1652461     DOI： 10.1016/0014-5793(91)80053-6

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  33 in total

Review 1.  Regulation by proteolysis: energy-dependent proteases and their targets.

Authors:  S Gottesman; M R Maurizi
Journal:  Microbiol Rev       Date:  1992-12

Review 2.  Slicing a protease: structural features of the ATP-dependent Lon proteases gleaned from investigations of isolated domains.

Authors:  Tatyana V Rotanova; Istvan Botos; Edward E Melnikov; Fatima Rasulova; Alla Gustchina; Michael R Maurizi; Alexander Wlodawer
Journal:  Protein Sci       Date:  2006-08       Impact factor: 6.725

3.  Cloning, nucleotide sequencing, and expression of the Azospirillum brasilense lon gene: involvement in iron uptake.

Authors:  E Mori; M Fulchieri; C Indorato; R Fani; M Bazzicalupo
Journal:  J Bacteriol       Date:  1996-06       Impact factor: 3.490

4.  Roles of the N domain of the AAA+ Lon protease in substrate recognition, allosteric regulation and chaperone activity.

Authors:  Matthew L Wohlever; Tania A Baker; Robert T Sauer
Journal:  Mol Microbiol       Date:  2013-11-10       Impact factor: 3.501

5.  Autocatalytic processing of the ATP-dependent PIM1 protease: crucial function of a pro-region for sorting to mitochondria.

Authors:  I Wagner; L van Dyck; A S Savel'ev; W Neupert; T Langer
Journal:  EMBO J       Date:  1997-12-15       Impact factor: 11.598

6.  The Lon protease-like domain in the bacterial RecA paralog RadA is required for DNA binding and repair.

Authors:  Masao Inoue; Kenji Fukui; Yuki Fujii; Noriko Nakagawa; Takato Yano; Seiki Kuramitsu; Ryoji Masui
Journal:  J Biol Chem       Date:  2017-04-21       Impact factor: 5.157

7.  Cloning, nucleotide sequence, and expression of the Bacillus subtilis lon gene.

Authors:  S Riethdorf; U Völker; U Gerth; A Winkler; S Engelmann; M Hecker
Journal:  J Bacteriol       Date:  1994-11       Impact factor: 3.490

8.  Binding and cleavage of E. coli HUbeta by the E. coli Lon protease.

Authors:  Jiahn-Haur Liao; Yu-Ching Lin; Jowey Hsu; Alan Yueh-Luen Lee; Tse-An Chen; Chun-Hua Hsu; Jiun-Ly Chir; Kuo-Feng Hua; Tzu-Hua Wu; Li-Jenn Hong; Pei-Wen Yen; Arthur Chiou; Shih-Hsiung Wu
Journal:  Biophys J       Date:  2010-01-06       Impact factor: 4.033

Review 9.  Functional mechanics of the ATP-dependent Lon protease- lessons from endogenous protein and synthetic peptide substrates.

Authors:  Irene Lee; Carolyn K Suzuki
Journal:  Biochim Biophys Acta       Date:  2008-03-05

10.  Cloning and nucleotide sequence of the Myxococcus xanthus lon gene: indispensability of lon for vegetative growth.

Authors:  N Tojo; S Inouye; T Komano
Journal:  J Bacteriol       Date:  1993-04       Impact factor: 3.490
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