Literature DB >> 1652385

Effects of bistramide A on a non-small-cell bronchial carcinoma line.

C Roussakis1, N Robillard, D Riou, J F Biard, G Pradal, P Piloquet, C Debitus, J F Verbist.   

Abstract

The antiproliferative effects of bistramide A, a nitrogenous dilactam polyether from Lissoclinum bistratum Sluiter (Urochordata), were studied at the level of the cell cycle in asynchronous cells of the NSCLCN6-L16 line. Bistramide A has a dual mechanism that induces blockade in the G1 phase (compatible with differentiation properties reported elsewhere) and causes polyploidy that is suggestive of inaptitude for cytokinesis. These effects confirm the results of cytomorphology studies in electron microscopy.

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Year:  1991        PMID： 1652385     DOI： 10.1007/bf00685536

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN： 0344-5704            Impact factor:   3.333


  9 in total

1.  Blockade of sodium channels by Bistramide A in voltage-clamped frog skeletal muscle fibres.

Authors:  M P Sauviat; D Gouiffes-Barbin; E Ecault; J F Verbist
Journal:  Biochim Biophys Acta       Date:  1992-01-10

2.  Pulse cytophotometric analysis of synchronized cells in vitro.

Authors:  B Barlogie; B Drewinko; D A Johnston; T Büchner; W H Hauss; E J Freireich
Journal:  Cancer Res       Date:  1976-03       Impact factor: 12.701

3.  Multi-user system for analysis of data from flow cytometry.

Authors:  J Fried; M Mandel
Journal:  Comput Programs Biomed       Date:  1979-12

4.  Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

Authors:  T Mosmann
Journal:  J Immunol Methods       Date:  1983-12-16       Impact factor: 2.303

5.  Study of the heterogeneity of a human non-small cell bronchopulmonary epidermoid primary carcinoma: determination of the DNA content of NSCLCN6L2 cells and of cloned sub-populations.

Authors:  C Gratas; N Robillard; C Roussakis; A F Audouin; J F Verbis
Journal:  Biol Cell       Date:  1990       Impact factor: 4.458

6.  Novel cytotoxic compounds from the ascidian Lissoclinum bistratum.

Authors:  B M Degnan; C J Hawkins; M F Lavin; E J McCaffrey; D L Parry; D J Watters
Journal:  J Med Chem       Date:  1989-06       Impact factor: 7.446

7.  The bistratenes: new cytotoxic marine macrolides which induce some properties indicative of differentiation in HL-60 cells.

Authors:  D Watters; K Marshall; S Hamilton; J Michael; M McArthur; G Seymour; C Hawkins; R Gardiner; M Lavin
Journal:  Biochem Pharmacol       Date:  1990-05-15       Impact factor: 5.858

8.  Flow microfluorometric analysis of nuclear DNA in cells from solid tumors and cell suspensions. A new method for rapid isolation and straining of nuclei.

Authors:  L L Vindelov
Journal:  Virchows Arch B Cell Pathol       Date:  1977-08-10

9.  Bistramide A, a new toxin from the urochordata Lissoclinum bistratum Sluiter: isolation and preliminary characterization.

Authors:  D Gouiffes; M Juge; N Grimaud; L Welin; M P Sauviat; Y Barbin; D Laurent; C Roussakis; J P Henichart; J F Verbist
Journal:  Toxicon       Date:  1988       Impact factor: 3.033
  9 in total
  3 in total

1.  Stimulation of protein kinase C-dependent and -independent signaling pathways by bistratene A in intestinal epithelial cells.

Authors:  M R Frey; O Leontieva; D J Watters; J D Black
Journal:  Biochem Pharmacol       Date:  2001-05-01       Impact factor: 5.858

2.  Accumulation of HL-60 leukemia cells in G2/M and inhibition of cytokinesis caused by two marine compounds, bistratene A and cycloxazoline.

Authors:  D J Watters; H J Beamish; K A Marshall; R A Gardiner; G J Seymour; M F Lavin
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

Review 3.  Marine Natural Products from New Caledonia--A Review.

Authors:  Sofia-Eléna Motuhi; Mohamed Mehiri; Claude Elisabeth Payri; Stéphane La Barre; Stéphane Bach
Journal:  Mar Drugs       Date:  2016-03-16       Impact factor: 5.118
  3 in total

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