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Literature DB >> 16522058

Myotube assembly on nanofibrous and micropatterned polymers.

Ngan F Huang¹, Shyam Patel, Rahul G Thakar, Jun Wu, Benjamin S Hsiao, Benjamin Chu, Randall J Lee, Song Li.

Abstract

Skeletal muscle consists of parallel bundles of myotubes formed by the fusion of myoblasts. We fabricated nanofibrous and micropatterned polymers as cell culture substrates to guide the morphogenesis of muscular tissue. The nanoscale and microscale topographic features regulate cell and cytoskeleton alignment, myotube assembly, myotube striation, and myoblast proliferation. This bottom-up approach from nanoscale to tissue level demonstrates the potential of nanofibrous polymers for engineering the assembly of cell and tissue structure.

Entities: Chemical Disease

Mesh：

Substances：
Polymers

Year: 2006 PMID： 16522058 DOI： 10.1021/nl060060o

Source DB: PubMed Journal: Nano Lett ISSN： 1530-6984 Impact factor: 11.189

Keyword Cloud
Cited

83 in total

1. Local tissue geometry determines contractile force generation of engineered muscle networks.

Authors: Weining Bian; Mark Juhas; Terry W Pfeiler; Nenad Bursac
Journal: Tissue Eng Part A Date: 2012-01-04 Impact factor: 3.845

2. In situ cross-linked electrospun fiber scaffold of collagen for fabricating cell-dense muscle tissue.

Authors: Naoya Takeda; Kenichi Tamura; Ryo Mineguchi; Yumiko Ishikawa; Yuji Haraguchi; Tatsuya Shimizu; Yusuke Hara
Journal: J Artif Organs Date: 2015-10-15 Impact factor: 1.731

Review 3. Biomaterials approach to expand and direct differentiation of stem cells.

Authors: Chou Chai; Kam W Leong
Journal: Mol Ther Date: 2007-01-30 Impact factor: 11.454

4. Anisotropic mechanosensing by mesenchymal stem cells.

Authors: Kyle Kurpinski; Julia Chu; Craig Hashi; Song Li
Journal: Proc Natl Acad Sci U S A Date: 2006-10-23 Impact factor: 11.205

5. Synthesis and characterization of ionic charged water soluble arginine-based poly(ester amide).

Authors: Jun Wu; Martha A Mutschler; Chih-Chang Chu
Journal: J Mater Sci Mater Med Date: 2011-02-03 Impact factor: 3.896

6. Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells.

Authors: Maureen Wanjare; Luqia Hou; Karina H Nakayama; Joseph J Kim; Nicholas P Mezak; Oscar J Abilez; Evangeline Tzatzalos; Joseph C Wu; Ngan F Huang
Journal: Biomater Sci Date: 2017-07-25 Impact factor: 6.843

Myotube assembly on nanofibrous and micropatterned polymers.

1. Local tissue geometry determines contractile force generation of engineered muscle networks.

2. In situ cross-linked electrospun fiber scaffold of collagen for fabricating cell-dense muscle tissue.

Review 3. Biomaterials approach to expand and direct differentiation of stem cells.

4. Anisotropic mechanosensing by mesenchymal stem cells.

5. Synthesis and characterization of ionic charged water soluble arginine-based poly(ester amide).

6. Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells.

Review 7. Polymers to direct cell fate by controlling the microenvironment.

Review 8. Microfabricated mammalian organ systems and their integration into models of whole animals and humans.

9. Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers.

10. Engineering the microstructure of electrospun fibrous scaffolds by microtopography.