[The effect of smoking on infertility treatment in women undergoing assisted reproduction cycles].

The aim of the present study was to investigate the influence of smoking on different parameters in woman treated by IVF-ICSI. The total number of MII stage oocytes retrieved, number of embryos, embryos quality and implantation rate were measured. 32 women undergoing IVF ICSI treatment were classified as smokers and 30 non-smokers on the basis of medical history. Smokers had decreased number of retrieved oocytes compared with non-smokers (p<0.05) and lower embryo score (p<0.05). There was no statistically significantly difference between quality of embryos in both groups. Women who smoked had also statistically significantly lower pregnancy rate per cycle (3% versus 38%) (p<0.000001). The knowledge gained from these results regarding the effects of female smoking on ART procedures may help to create guidelines for clinicians and providing a forceful impetus for women undergoing IVF-ICSI to stop smoking.