OBJECTIVE: A retrospective analysis of the epidemiology and intensive care treatment of ARDS in Iceland during the 10 year period, 1988-1997 with observation of trends within the period. MATERIAL AND METHODS: All ICU admissions in Iceland 1988-1997 were reviewed according to the American-European consensus conference criteria on ARDS to select patients with the diagnosis of ARDS i.e. bilateral pulmonary infiltrates, PaO(2)/FiO(2) <200 and excluding patients with signs of heart failure or a pulmonary capillary wedge pressure (PCWP) >18 mmHg. Data were collected on age, gender, length of stay, ventilator treatment and ventilatory modes, causes of ARDS and mortality. RESULTS: A total of 220 patients with severe respiratory failure were found and 155 of them were diagnosed as having ARDS or an annual incidence of 15.5 cases/year or 5.9 cases/100.000/year. If reference population >15 years of age is used for calculation the incidence is 7.8 cases/100.000/year. Hospital mortality was 40%, mean length of ICU stay was 21 days, mean hospital length of stay 39 days. The incidence of ARDS increased during the period with a tendency to lower mortality rates. Mortality was significantly lower when pressure controlled ventilation was used, compared to volume controlled ventilation. CONCLUSION: The incidence of ARDS in a well defined population of Iceland is lower than recent studies in USA and Europe have shown or 5.9 cases/100.00/year but is increasing. The mortality is 40% and shows a slight downward trend, which may be due to the use of lung protective ventilation.
OBJECTIVE: A retrospective analysis of the epidemiology and intensive care treatment of ARDS in Iceland during the 10 year period, 1988-1997 with observation of trends within the period. MATERIAL AND METHODS: All ICU admissions in Iceland 1988-1997 were reviewed according to the American-European consensus conference criteria on ARDS to select patients with the diagnosis of ARDS i.e. bilateral pulmonary infiltrates, PaO(2)/FiO(2) <200 and excluding patients with signs of heart failure or a pulmonary capillary wedge pressure (PCWP) >18 mmHg. Data were collected on age, gender, length of stay, ventilator treatment and ventilatory modes, causes of ARDS and mortality. RESULTS: A total of 220 patients with severe respiratory failure were found and 155 of them were diagnosed as having ARDS or an annual incidence of 15.5 cases/year or 5.9 cases/100.000/year. If reference population >15 years of age is used for calculation the incidence is 7.8 cases/100.000/year. Hospital mortality was 40%, mean length of ICU stay was 21 days, mean hospital length of stay 39 days. The incidence of ARDS increased during the period with a tendency to lower mortality rates. Mortality was significantly lower when pressure controlled ventilation was used, compared to volume controlled ventilation. CONCLUSION: The incidence of ARDS in a well defined population of Iceland is lower than recent studies in USA and Europe have shown or 5.9 cases/100.00/year but is increasing. The mortality is 40% and shows a slight downward trend, which may be due to the use of lung protective ventilation.