| Literature DB >> 16518571 |
Bard Ermentrout1, David Saunders.
Abstract
A number of experimental groups have recently computed Phase Response Curves (PRCs) for neurons. There is a great deal of noise in the data. We apply methods from stochastic nonlinear dynamics to coupled noisy phase-resetting maps and obtain the invariant density of phase distributions. By exploiting the special structure of PRCs, we obtain some approximations for the invariant distributions. Comparisons to Monte-Carlo simulations are made. We show how phase-dependence of the noise can move the peak of the invariant density away from the peak expected from the analysis of the deterministic system and thus lead to noise-induced bifurcations.Mesh:
Year: 2006 PMID: 16518571 DOI: 10.1007/s10827-005-5427-0
Source DB: PubMed Journal: J Comput Neurosci ISSN: 0929-5313 Impact factor: 1.621