Literature DB >> 16518413

Importance of the bone marrow microenvironment in inducing the angiogenic response in multiple myeloma.

D Ribatti1, B Nico, A Vacca.   

Abstract

Tumor microenvironment is essential for tumor cell proliferation, angiogenesis, invasion and metastasis through its provision of survival signals, secretion of growth and pro-angiogenic factors, and direct adhesion molecule interactions. This review examines its importance in the induction of an angiogenic response in multiple myeloma (MM). The encouraging results of preclinical and clinical trials in which MM has been treated by targeting the tumor microenvironment are also discussed.

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Year:  2006        PMID: 16518413     DOI: 10.1038/sj.onc.1209456

Source DB:  PubMed          Journal:  Oncogene        ISSN: 0950-9232            Impact factor:   9.867


  55 in total

Review 1.  The use of molecular-based risk stratification and pharmacogenomics for outcome prediction and personalized therapeutic management of multiple myeloma.

Authors:  Sarah K Johnson; Christoph J Heuck; Anthony P Albino; Pingping Qu; Qing Zhang; Bart Barlogie; John D Shaughnessy
Journal:  Int J Hematol       Date:  2011-10-15       Impact factor: 2.490

2.  Osteoclasts are important for bone angiogenesis.

Authors:  Frank C Cackowski; Judith L Anderson; Kenneth D Patrene; Rushir J Choksi; Steven D Shapiro; Jolene J Windle; Harry C Blair; G David Roodman
Journal:  Blood       Date:  2009-11-03       Impact factor: 22.113

Review 3.  Macrophages in multiple myeloma: key roles and therapeutic strategies.

Authors:  Khatora S Opperman; Kate Vandyke; Peter J Psaltis; Jacqueline E Noll; Andrew C W Zannettino
Journal:  Cancer Metastasis Rev       Date:  2021-01-06       Impact factor: 9.264

Review 4.  Macrophages in multiple myeloma: emerging concepts and therapeutic implications.

Authors:  Fotis Asimakopoulos; Jaehyup Kim; Ryan A Denu; Chelsea Hope; Jeffrey L Jensen; Samuel J Ollar; Ellen Hebron; Claire Flanagan; Natalie Callander; Peiman Hematti
Journal:  Leuk Lymphoma       Date:  2013-04-11

5.  Bone marrow angiogenesis and progression in multiple myeloma.

Authors:  Roberto Ria; Antonia Reale; Annunziata De Luisi; Arianna Ferrucci; Michele Moschetta; Angelo Vacca
Journal:  Am J Blood Res       Date:  2011-06-08

Review 6.  Identify multiple myeloma stem cells: Utopia?

Authors:  Ilaria Saltarella; Aurelia Lamanuzzi; Antonia Reale; Angelo Vacca; Roberto Ria
Journal:  World J Stem Cells       Date:  2015-01-26       Impact factor: 5.326

7.  Impaired efferocytosis by monocytes in multiple myeloma.

Authors:  Ying Yu Liang; Ilse Schwarzinger; Ingrid Simonitsch-Klupp; Hermine Agis; Rudolf Oehler
Journal:  Oncol Lett       Date:  2018-05-02       Impact factor: 2.967

8.  Tie2 signaling regulates osteoclastogenesis and osteolytic bone invasion of breast cancer.

Authors:  Yongfen Min; Xiubao Ren; David B Vaught; Jin Chen; Edwin Donnelly; Conor C Lynch; P Charles Lin
Journal:  Cancer Res       Date:  2010-03-16       Impact factor: 12.701

9.  Constitutive expression of IL-12R beta 2 on human multiple myeloma cells delineates a novel therapeutic target.

Authors:  Irma Airoldi; Claudia Cocco; Nicola Giuliani; Marina Ferrarini; Simona Colla; Emanuela Ognio; Giuseppe Taverniti; Emma Di Carlo; Giovanna Cutrona; Vittorio Perfetti; Vittorio Rizzoli; Domenico Ribatti; Vito Pistoia
Journal:  Blood       Date:  2008-05-12       Impact factor: 22.113

Review 10.  Active versus passive mechanisms in metastasis: do cancer cells crawl into vessels, or are they pushed?

Authors:  Maximilian Bockhorn; Rakesh K Jain; Lance L Munn
Journal:  Lancet Oncol       Date:  2007-05       Impact factor: 41.316

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