| Literature DB >> 16518338 |
Abstract
Toll-like receptors (TLRs) recognize both exogenous microbial components and endogenous molecules to promote immune activation. Both immune and nonimmune renal cells express TLRs, which are involved in the pathogenesis of a number of kidney diseases, including pyelonephritis, Leptospira nephritis, immune-complex glomerulonephritis, ischemic/reperfusion injury, and rejection of kidney transplant.Entities:
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Year: 2006 PMID: 16518338 DOI: 10.1038/sj.ki.5000190
Source DB: PubMed Journal: Kidney Int ISSN: 0085-2538 Impact factor: 10.612