Literature DB >> 16517203

Lessons learned from molecular defects in nuclear factor kappaB dependent signaling.

Douglas R McDonald1, Riny Janssen, Raif Geha.   

Abstract

Nuclear factor (NF) kappaB is a ubiquitously expressed transcription factor that plays critical roles in normal development and inflammation. Characterization of naturally occurring defects in signaling pathways leading to activation of NFkappaB, complemented by mouse knockout models, has demonstrated the vital role of NFkappaB in normal host defense.

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Year:  2006        PMID： 16517203     DOI： 10.1016/j.micinf.2005.10.030

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  5 in total

1.  Dynamic changes in pro- and anti-inflammatory cytokine profiles and gamma interferon receptor signaling integrity correlate with tuberculosis disease activity and response to curative treatment.

Authors:  Edhyana Sahiratmadja; Bachti Alisjahbana; Tjitske de Boer; Iskandar Adnan; Anugrah Maya; Halim Danusantoso; Ronald H H Nelwan; Sangkot Marzuki; Jos W M van der Meer; Reinout van Crevel; Esther van de Vosse; Tom H M Ottenhoff
Journal:  Infect Immun       Date:  2006-12-04       Impact factor: 3.441

2.  Mycobacterium abscessus and M. avium trigger Toll-like receptor 2 and distinct cytokine response in human cells.

Authors:  Elizabeth P Sampaio; Houda Z Elloumi; Adrian Zelazny; Li Ding; Michelle L Paulson; Alan Sher; Andre L Bafica; Yvonne R Shea; Steven M Holland
Journal:  Am J Respir Cell Mol Biol       Date:  2008-04-25       Impact factor: 6.914

Review 3.  The zinc finger domain of IKKγ (NEMO) protein in health and disease.

Authors:  Amde Selassie Shifera
Journal:  J Cell Mol Med       Date:  2010-10       Impact factor: 5.310

Review 4.  The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency.

Authors:  Stuart E Turvey; Anne Durandy; Alain Fischer; Shan-Yu Fung; Raif S Geha; Andreas Gewies; Thomas Giese; Johann Greil; Bärbel Keller; Margaret L McKinnon; Bénédicte Neven; Jacob Rozmus; Jürgen Ruland; Andrew L Snow; Polina Stepensky; Klaus Warnatz
Journal:  J Allergy Clin Immunol       Date:  2014-08       Impact factor: 10.793

5.  The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling.

Authors:  Theo Klein; Shan-Yu Fung; Florian Renner; Michael A Blank; Antoine Dufour; Sohyeong Kang; Madison Bolger-Munro; Joshua M Scurll; John J Priatel; Patrick Schweigler; Samu Melkko; Michael R Gold; Rosa I Viner; Catherine H Régnier; Stuart E Turvey; Christopher M Overall
Journal:  Nat Commun       Date:  2015-11-03       Impact factor: 14.919
  5 in total

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