| Literature DB >> 16516254 |
Edward Rubenstein1, Haihong Zhou, Karolina M Krasinska, Allis Chien, Christopher H Becker.
Abstract
Azetidine-2-carboxylic acid (L-Aze) is a toxic and teratogenic non-protein amino acid. In many species, including man, L-Aze is misincorporated into protein in place of proline, altering collagen, keratin, hemoglobin, and protein folding. In animal models of teratogenesis, it causes a wide range of malformations. The role of L-Aze in human disease has been unexplored, probably because the compound has not been associated with foods consumed by humans. Herein we report the presence of L-Aze in the garden or table beet (Beta vulgaris).Entities:
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Year: 2006 PMID： 16516254 DOI： 10.1016/j.phytochem.2006.01.028
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072