Literature DB >> 16513393

Genetic host resistance and susceptibility to leprosy.

Marcelo Távora Mira1.   

Abstract

Leprosy is a chronic infectious disease that affects 600,000 new individuals worldwide every year. This article summarizes some of the advances achieved over the past decades towards the description of the exact number, location and nature of the genetic variants responsible for the well established genetic component controlling leprosy susceptibility in humans.

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Year:  2006        PMID： 16513393     DOI： 10.1016/j.micinf.2005.10.024

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  17 in total

1.  Genetic variants of the MRC1 gene and the IFNG gene are associated with leprosy in Han Chinese from Southwest China.

Authors:  Dong Wang; Jia-Qi Feng; Yu-Ye Li; Deng-Feng Zhang; Xiao-An Li; Qing-Wei Li; Yong-Gang Yao
Journal:  Hum Genet       Date:  2012-03-06       Impact factor: 4.132

Review 2.  Leprosy as a genetic disease.

Authors:  Andrea Alter; Audrey Grant; Laurent Abel; Alexandre Alcaïs; Erwin Schurr
Journal:  Mamm Genome       Date:  2010-10-09       Impact factor: 2.957

3.  Human leukocyte antigen class I region single-nucleotide polymorphisms are associated with leprosy susceptibility in Vietnam and India.

Authors:  Andrea Alter; Nguyen Thu Huong; Meenakshi Singh; Marianna Orlova; Nguyen Van Thuc; Kiran Katoch; Xiaojiang Gao; Vu Hong Thai; Nguyen Ngoc Ba; Mary Carrington; Laurent Abel; Narinder Mehra; Alexandre Alcaïs; Erwin Schurr
Journal:  J Infect Dis       Date:  2011-05-01       Impact factor: 5.226

4.  Mannan-binding lectin plasma levels in leprosy: deficiency confers protection against the lepromatous but not the tuberculoid forms.

Authors:  L N Dornelles; L Pereira-Ferrari; I Messias-Reason
Journal:  Clin Exp Immunol       Date:  2006-09       Impact factor: 4.330

5.  HLA-DR and HLA-DQ alleles in patients from the south of Brazil: markers for leprosy susceptibility and resistance.

Authors:  Samira A da Silva; Priscila S Mazini; Pâmela G Reis; Ana M Sell; Luiza T Tsuneto; Paulo R Peixoto; Jeane E L Visentainer
Journal:  BMC Infect Dis       Date:  2009-08-22       Impact factor: 3.090

6.  Polymorphisms in Toll-like receptor 4 (TLR4) are associated with protection against leprosy.

Authors:  P-Y Bochud; D Sinsimer; A Aderem; M R Siddiqui; P Saunderson; S Britton; I Abraham; A Tadesse Argaw; M Janer; T R Hawn; G Kaplan
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2009-05-09       Impact factor: 3.267

Review 7.  Leprosy as a genetic model for susceptibility to common infectious diseases.

Authors:  Andrea Alter; Alexandre Alcaïs; Laurent Abel; Erwin Schurr
Journal:  Hum Genet       Date:  2008-02-05       Impact factor: 4.132

8.  New insights in the pathogenesis and genetics of leprosy.

Authors:  Andrea Gulia; Isabella Fried; Cesare Massone
Journal:  F1000 Med Rep       Date:  2010-04-27

9.  Human polymorphisms as clinical predictors in leprosy.

Authors:  Ernesto Prado Montes de Oca
Journal:  J Trop Med       Date:  2011-12-18

10.  PARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages.

Authors:  Louis de Léséleuc; Marianna Orlova; Aurelie Cobat; Manon Girard; Nguyen Thu Huong; Nguyen Ngoc Ba; Nguyen Van Thuc; Richard Truman; John S Spencer; Linda Adams; Vu Hong Thai; Alexandre Alcais; Erwin Schurr
Journal:  PLoS Negl Trop Dis       Date:  2013-01-17
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