Literature DB >> 16513380

Genetic analysis of host resistance to intracellular pathogens: lessons from studies of Toxoplasma gondii infection.

George S Yap1, Michael H Shaw, Yun Ling, Alan Sher.   

Abstract

Cell-mediated immunity to Toxoplasma gondii establishes and maintains a balanced host-pathogen relationship. Recent analyses using spontaneous and genetically engineered mouse mutants have yielded a clearer picture of factors positively and negatively regulating the host immune response and a better understanding of cytokine-inducible intracytoplasmic mechanisms that lead to intracellular pathogen suppression and demise.

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Year:  2006        PMID： 16513380     DOI： 10.1016/j.micinf.2005.10.031

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  17 in total

1.  Serologic evidence that ascaris and toxoplasma infections impact inflammatory responses to Helicobacter pylori in Colombians.

Authors:  Courtney Ek; Mark T Whary; Melanie Ihrig; Luis E Bravo; Pelayo Correa; James G Fox
Journal:  Helicobacter       Date:  2012-04       Impact factor: 5.753

2.  Externally triggered egress is the major fate of Toxoplasma gondii during acute infection.

Authors:  Tadakimi Tomita; Tatsuya Yamada; Louis M Weiss; Amos Orlofsky
Journal:  J Immunol       Date:  2009-10-21       Impact factor: 5.422

3.  Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells.

Authors:  Florence Dzierszinski; Marion Pepper; Jason S Stumhofer; David F LaRosa; Emma H Wilson; Laurence A Turka; Sandra K Halonen; Christopher A Hunter; David S Roos
Journal:  Infect Immun       Date:  2007-09-10       Impact factor: 3.441

4.  Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence.

Authors:  Sarah J Fentress; Michael S Behnke; Ildiko R Dunay; Mona Mashayekhi; Leah M Rommereim; Barbara A Fox; David J Bzik; Gregory A Taylor; Benjamin E Turk; Cheryl F Lichti; R Reid Townsend; Wei Qiu; Raymond Hui; Wandy L Beatty; L David Sibley
Journal:  Cell Host Microbe       Date:  2010-12-16       Impact factor: 21.023

Review 5.  The secreted kinase ROP18 defends Toxoplasma's border.

Authors:  Sarah J Fentress; L David Sibley
Journal:  Bioessays       Date:  2011-07-20       Impact factor: 4.345

6.  Macrophage migration inhibitory factor (MIF) is critical for the host resistance against Toxoplasma gondii.

Authors:  Marcos Flores; Rafael Saavedra; Rocio Bautista; Rubi Viedma; Eda P Tenorio; Lin Leng; Yuriko Sánchez; Imelda Juárez; Anjali A Satoskar; Asha S Shenoy; Luis I Terrazas; Richard Bucala; Joseph Barbi; Abhay R Satoskar; Miriam Rodriguez-Sosa
Journal:  FASEB J       Date:  2008-07-07       Impact factor: 5.191

7.  Phosphoinositide-3-kinase-dependent, MyD88-independent induction of CC-type chemokines characterizes the macrophage response to Toxoplasma gondii strains with high virulence.

Authors:  Chiang W Lee; Woraporn Sukhumavasi; Eric Y Denkers
Journal:  Infect Immun       Date:  2007-10-01       Impact factor: 3.441

8.  Co-existence of classical and alternative activation programs in macrophages responding to Toxoplasma gondii.

Authors:  Veerupaxagouda Patil; Yanlin Zhao; Suhagi Shah; Barbara A Fox; Leah M Rommereim; David J Bzik; George S Yap
Journal:  Int J Parasitol       Date:  2013-09-29       Impact factor: 3.981

Review 9.  The known unknowns of antigen processing and presentation.

Authors:  Jatin M Vyas; Annemarthe G Van der Veen; Hidde L Ploegh
Journal:  Nat Rev Immunol       Date:  2008-08       Impact factor: 53.106

10.  A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.

Authors:  Masahiro Yamamoto; Daron M Standley; Seiji Takashima; Hiroyuki Saiga; Megumi Okuyama; Hisako Kayama; Emi Kubo; Hiroshi Ito; Mutsumi Takaura; Tadashi Matsuda; Dominique Soldati-Favre; Kiyoshi Takeda
Journal:  J Exp Med       Date:  2009-11-09       Impact factor: 14.307
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