Literature DB >> 16513348

Anti-angiogenic activity of basic-type, selective cyclooxygenase (COX)-1 inhibitors.

Hiroko Sano1, Tomomi Noguchi, Atsushi Miyajima, Yuichi Hashimoto, Hiroyuki Miyachi.   

Abstract

Indole- and indoline-type basic COX-1-selective competitive inhibitors, 5-amino-1-(3,5-dimethylbenzoyl)-1H-indole (1) and 5-amino-1-(3,5-dimethylphenyl)-2,3-dihydro-1H-indole (2), were found to possess anti-angiogenic activity estimated as a tube formation-inhibition using human umbilical vein endothelial cells (HUVECs).

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Year:  2006        PMID： 16513348     DOI： 10.1016/j.bmcl.2006.02.021

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  The effects of nepafenac and amfenac on retinal angiogenesis.

Authors:  Susan E Yanni; Monika L Clark; Rong Yang; David P Bingaman; John S Penn
Journal:  Brain Res Bull       Date:  2009-11-06       Impact factor: 4.077

2.  Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines.

Authors:  Ibrahim Jantan; Syed Nasir Abbas Bukhari; Olayiwola A Adekoya; Ingebrigt Sylte
Journal:  Drug Des Devel Ther       Date:  2014-09-16       Impact factor: 4.162

3.  A Quick Access to Structurally Diverse Triazoloquinazoline Heterocycles via the MIL-101(Cr)-Catalyzed One-Pot Multi-Component Reaction of a Series of Benzaldehydes, Dimedone, and 1H-1,2,4-Triazol-3-Amine Under Green Conditions.

Authors:  Pezhman Shiri; Esmaeil Niknam; Jasem Aboonajmi; Ali Khalafi-Nezhad; Ali Mohammad Amani
Journal:  Front Chem       Date:  2022-07-25       Impact factor: 5.545
  3 in total

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