| Literature DB >> 16513327 |
M Nonaka1, H Ikeda, A Fujisawa, M Uehara, T Inokuchi.
Abstract
The present study investigated induction of apoptosis in NB-1 oral carcinoma cells by paclitaxel and the expression of Bcl-2 and Bax in relation to this apoptotic cell death. Paclitaxel induced apoptotic cell death in NB-1 cells in a dose- and a time-dependent manner. The present results suggest that paclitaxel can induce apoptosis of NB-1 cells, which may be mediated by down-regulation of Bcl-2 together with up-regulation of Bax.Entities:
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Year: 2006 PMID： 16513327 DOI： 10.1016/j.ijom.2006.01.011
Source DB: PubMed Journal: Int J Oral Maxillofac Surg ISSN： 0901-5027 Impact factor: 2.789