| Literature DB >> 16511933 |
Andrew J K Ostör1, Edwin R Chilvers, Margaret F Somerville, Anita Y N Lim, Suzanne E Lane, Adrian J Crisp, David G I Scott.
Abstract
We describe 5 patients with rheumatoid arthritis (RA) who developed pulmonary complications following infliximab therapy; 4 patients had preexisting usual interstitial pneumonia. As the pathophysiology of the pulmonary insult is unknown, we advise caution in the use of anti-tumor necrosis factor-alpha therapy in patients with RA with underlying lung disease of sufficient severity to withhold methotrexate treatment.Entities:
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Year: 2006 PMID: 16511933
Source DB: PubMed Journal: J Rheumatol ISSN: 0315-162X Impact factor: 4.666