Literature DB >> 16511594

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease.

Brian N Finck1, Daniel P Kelly.   

Abstract

Members of the PPARgamma coactivator-1 (PGC-1) family of transcriptional coactivators serve as inducible coregulators of nuclear receptors in the control of cellular energy metabolic pathways. This Review focuses on the biologic and physiologic functions of the PGC-1 coactivators, with particular emphasis on striated muscle, liver, and other organ systems relevant to common diseases such as diabetes and heart failure.

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Year:  2006        PMID： 16511594      PMCID： PMC1386111          DOI： 10.1172/JCI27794

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  89 in total

Review 1.  PGC-1, a versatile coactivator.

Authors:  D Knutti; A Kralli
Journal:  Trends Endocrinol Metab       Date:  2001-10       Impact factor: 12.015

2.  Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor.

Authors:  D Knutti; D Kressler; A Kralli
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-31       Impact factor: 11.205

3.  CREB regulates hepatic gluconeogenesis through the coactivator PGC-1.

Authors:  S Herzig; F Long; U S Jhala; S Hedrick; R Quinn; A Bauer; D Rudolph; G Schutz; C Yoon; P Puigserver; B Spiegelman; M Montminy
Journal:  Nature       Date:  2001-09-13       Impact factor: 49.962

4.  Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1.

Authors:  J C Yoon; P Puigserver; G Chen; J Donovan; Z Wu; J Rhee; G Adelmant; J Stafford; C R Kahn; D K Granner; C B Newgard; B M Spiegelman
Journal:  Nature       Date:  2001-09-13       Impact factor: 49.962

5.  Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1.

Authors:  P Puigserver; J Rhee; J Lin; Z Wu; J C Yoon; C Y Zhang; S Krauss; V K Mootha; B B Lowell; B M Spiegelman
Journal:  Mol Cell       Date:  2001-11       Impact factor: 17.970

6.  Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor.

Authors:  Jiandie Lin; Pere Puigserver; Jerry Donovan; Paul Tarr; Bruce M Spiegelman
Journal:  J Biol Chem       Date:  2001-11-30       Impact factor: 5.157

Review 7.  Transcriptional activation of energy metabolic switches in the developing and hypertrophied heart.

Authors:  John J Lehman; Daniel P Kelly
Journal:  Clin Exp Pharmacol Physiol       Date:  2002-04       Impact factor: 2.557

Review 8.  Gene regulatory mechanisms governing energy metabolism during cardiac hypertrophic growth.

Authors:  John J Lehman; Daniel P Kelly
Journal:  Heart Fail Rev       Date:  2002-04       Impact factor: 4.214

9.  Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus.

Authors:  J Ek; G Andersen; S A Urhammer; P H Gaede; T Drivsholm; K Borch-Johnsen; T Hansen; O Pedersen
Journal:  Diabetologia       Date:  2001-12       Impact factor: 10.122

10.  The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha.

Authors:  Dieter Kressler; Sylvia N Schreiber; Darko Knutti; Anastasia Kralli
Journal:  J Biol Chem       Date:  2002-02-19       Impact factor: 5.157
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  556 in total

Review 1.  Role of NYGGF4 in insulin resistance.

Authors:  Xiaoling Chen; Zhiqing Huang; Daiwen Chen; Gang Jia; Xiangbing Mao; Xiuqun Wu
Journal:  Mol Biol Rep       Date:  2011-12-13       Impact factor: 2.316

2.  Kinase suppressor of ras 1 (KSR1) regulates PGC1α and estrogen-related receptor α to promote oncogenic Ras-dependent anchorage-independent growth.

Authors:  Kurt W Fisher; Binita Das; Robert L Kortum; Oleg V Chaika; Robert E Lewis
Journal:  Mol Cell Biol       Date:  2011-04-25       Impact factor: 4.272

3.  Circadian metabolic regulation through crosstalk between casein kinase 1δ and transcriptional coactivator PGC-1α.

Authors:  Siming Li; Xiao-Wei Chen; Lei Yu; Alan R Saltiel; Jiandie D Lin
Journal:  Mol Endocrinol       Date:  2011-11-03

4.  Increasing the level of peroxisome proliferator-activated receptor γ coactivator-1α in podocytes results in collapsing glomerulopathy.

Authors:  Szu-Yuan Li; Jihwan Park; Chengxiang Qiu; Seung Hyeok Han; Matthew B Palmer; Zoltan Arany; Katalin Susztak
Journal:  JCI Insight       Date:  2017-07-20

5.  Regulatory circuitry of TWEAK-Fn14 system and PGC-1α in skeletal muscle atrophy program.

Authors:  Sajedah M Hindi; Vivek Mishra; Shephali Bhatnagar; Marjan M Tajrishi; Yuji Ogura; Zhen Yan; Linda C Burkly; Timothy S Zheng; Ashok Kumar
Journal:  FASEB J       Date:  2013-12-10       Impact factor: 5.191

6.  Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation.

Authors:  Sarah Sczelecki; Aurèle Besse-Patin; Alexandra Abboud; Sandra Kleiner; Dina Laznik-Bogoslavski; Christiane D Wrann; Jorge L Ruas; Benjamin Haibe-Kains; Jennifer L Estall
Journal:  Am J Physiol Endocrinol Metab       Date:  2013-11-26       Impact factor: 4.310

Review 7.  Hepatocyte nuclear factor 4alpha regulation of bile acid and drug metabolism.

Authors:  John Y L Chiang
Journal:  Expert Opin Drug Metab Toxicol       Date:  2009-02       Impact factor: 4.481

8.  Effect of Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 Alpha Variants on Spontaneous Clearance and Fibrosis Progression during Hepatitis C Virus Infection in Moroccan Patients.

Authors:  Raouia ElFihry; Mohcine Elmessaoudi-Idrissi; Fatima-Zahra Jadid; Imane Zaidane; Hajar Chihab; Mohamed Tahiri; Mostafa Kabine; Wafaa Badre; Isabelle Chemin; Agnes Marchio; Pascal Pineau; Sayeh Ezzikouri; Soumaya Benjelloun
Journal:  Virol Sin       Date:  2020-04-15       Impact factor: 4.327

Review 9.  Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator.

Authors:  Richard C Scarpulla
Journal:  Ann N Y Acad Sci       Date:  2008-12       Impact factor: 5.691

Review 10.  Caloric restriction and aging: studies in mice and monkeys.

Authors:  Rozalyn M Anderson; Dhanansayan Shanmuganayagam; Richard Weindruch
Journal:  Toxicol Pathol       Date:  2008-12-15       Impact factor: 1.902
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