Literature DB >> 16511396

Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis.

Rima McLeod1, Asif Rashid Khan, Gwendolyn A Noble, Paul Latkany, Jessica Jalbrzikowski, Kenneth Boyer.   

Abstract

A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines. Symptoms resolved when systemic corticosteroids were administered. This case underscores problems in clinical management with sulfadiazine hypersensitivity, potential immunosuppression from corticosteroids and selection of medications for recurrences of toxoplasmic chorioretinitis.

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Year:  2006        PMID: 16511396     DOI: 10.1097/01.inf.0000202070.59190.9a

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN: 0891-3668            Impact factor:   2.129


  18 in total

1.  In vitro antagonistic and indifferent activity of combination of 3-deoxyanthocyanidins against Toxoplasma gondii.

Authors:  Daniel A Abugri; William H Witola; Jesse M Jaynes
Journal:  Parasitol Res       Date:  2017-10-30       Impact factor: 2.289

2.  Discovery of Potent and Selective Leads against Toxoplasma gondii Dihydrofolate Reductase via Structure-Based Design.

Authors:  Matthew E Welsch; Jian Zhou; Yueqiang Gao; Yunqing Yan; Gene Porter; Gautam Agnihotri; Yingjie Li; Henry Lu; Zhongguo Chen; Stephen B Thomas
Journal:  ACS Med Chem Lett       Date:  2016-09-17       Impact factor: 4.345

Review 3.  Unravelling Toxoplasma treatment: conventional drugs toward nanomedicine.

Authors:  Sanaz Jafarpour Azami; Hanieh Mohammad Rahimi; Hamed Mirjalali; Mohammad Reza Zali
Journal:  World J Microbiol Biotechnol       Date:  2021-02-10       Impact factor: 3.312

4.  Salicylanilide inhibitors of Toxoplasma gondii.

Authors:  Alina Fomovska; Richard D Wood; Ernest Mui; Jitenter P Dubey; Leandra R Ferreira; Mark R Hickman; Patricia J Lee; Susan E Leed; Jennifer M Auschwitz; William J Welsh; Caroline Sommerville; Stuart Woods; Craig Roberts; Rima McLeod
Journal:  J Med Chem       Date:  2012-09-26       Impact factor: 7.446

5.  Rapid discovery of inhibitors of Toxoplasma gondii using hybrid structure-based computational approach.

Authors:  Sandhya Kortagere; Ernest Mui; Rima McLeod; William J Welsh
Journal:  J Comput Aided Mol Des       Date:  2011-02-26       Impact factor: 3.686

6.  Identification and development of novel inhibitors of Toxoplasma gondii enoyl reductase.

Authors:  Suresh K Tipparaju; Stephen P Muench; Ernest J Mui; Sergey N Ruzheinikov; Jeffrey Z Lu; Samuel L Hutson; Michael J Kirisits; Sean T Prigge; Craig W Roberts; Fiona L Henriquez; Alan P Kozikowski; David W Rice; Rima L McLeod
Journal:  J Med Chem       Date:  2010-09-09       Impact factor: 7.446

7.  Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase.

Authors:  Gang Cheng; Stephen P Muench; Ying Zhou; Gustavo A Afanador; Ernest J Mui; Alina Fomovska; Bo Shiun Lai; Sean T Prigge; Stuart Woods; Craig W Roberts; Mark R Hickman; Patty J Lee; Susan E Leed; Jennifer M Auschwitz; David W Rice; Rima McLeod
Journal:  Bioorg Med Chem Lett       Date:  2013-02-13       Impact factor: 2.823

8.  Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.

Authors:  Gustavo A Afanador; Stephen P Muench; Martin McPhillie; Alina Fomovska; Arne Schön; Ying Zhou; Gang Cheng; Jozef Stec; Joel S Freundlich; Hong-Ming Shieh; John W Anderson; David P Jacobus; David A Fidock; Alan P Kozikowski; Colin W Fishwick; David W Rice; Ernesto Freire; Rima McLeod; Sean T Prigge
Journal:  Biochemistry       Date:  2013-12-13       Impact factor: 3.162

9.  Spiroindolone that inhibits PfATPase4 is a potent, cidal inhibitor of Toxoplasma gondii tachyzoites in vitro and in vivo.

Authors:  Ying Zhou; Alina Fomovska; Stephen Muench; Bo-Shiun Lai; Ernest Mui; Rima McLeod
Journal:  Antimicrob Agents Chemother       Date:  2013-12-23       Impact factor: 5.191

Review 10.  Why prevent, diagnose and treat congenital toxoplasmosis?

Authors:  Rima McLeod; Francois Kieffer; Mari Sautter; Tiffany Hosten; Herve Pelloux
Journal:  Mem Inst Oswaldo Cruz       Date:  2009-03       Impact factor: 2.743

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