Literature DB >> 16511123

Crystallization and X-ray crystallographic analysis of human STAT1.

Xiang Mao1, Xiaomin Chen.   

Abstract

Unphosphorylated human STAT1 (1-683) has been crystallized in the presence of a phosphopeptide derived from the alpha-chain of human interferon gamma (IFNgamma) receptor. A complete data set has been collected from a KAu(CN)2-derivatized and dehydrated crystal. The crystal belonged to space group P6(1)22, with unit-cell parameters a = b = 102.6, c = 646.5 A, alpha = beta = 90, gamma = 120 degrees.

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Year:  2005        PMID： 16511123      PMCID： PMC1952444          DOI： 10.1107/S1744309105017392

Source DB:  PubMed          Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun        ISSN： 1744-3091


  18 in total

Review 1.  STAT proteins: signal tranducers and activators of transcription.

Authors:  J Bromberg; X Chen
Journal:  Methods Enzymol       Date:  2001       Impact factor: 1.600

2.  A reinterpretation of the dimerization interface of the N-terminal domains of STATs.

Authors:  Xiaomin Chen; Rashna Bhandari; Uwe Vinkemeier; Focco Van Den Akker; James E Darnell; John Kuriyan
Journal:  Protein Sci       Date:  2003-02       Impact factor: 6.725

3.  Dehydration converts DsbG crystal diffraction from low to high resolution.

Authors:  Begoña Heras; Melissa A Edeling; Karl A Byriel; Alun Jones; Satish Raina; Jennifer L Martin
Journal:  Structure       Date:  2003-02       Impact factor: 5.006

4.  STATs dimerize in the absence of phosphorylation.

Authors:  Jutta Braunstein; Siska Brutsaert; Rich Olson; Christian Schindler
Journal:  J Biol Chem       Date:  2003-06-28       Impact factor: 5.157

Review 5.  Stats: transcriptional control and biological impact.

Authors:  David E Levy; J E Darnell
Journal:  Nat Rev Mol Cell Biol       Date:  2002-09       Impact factor: 94.444

6.  Structural bases of unphosphorylated STAT1 association and receptor binding.

Authors:  Xiang Mao; Zhiyong Ren; Gregory N Parker; Holger Sondermann; Michael A Pastorello; Wei Wang; John S McMurray; Borries Demeler; James E Darnell; Xiaomin Chen
Journal:  Mol Cell       Date:  2005-03-18       Impact factor: 17.970

7.  Processing of X-ray diffraction data collected in oscillation mode.

Authors:  Z Otwinowski; W Minor
Journal:  Methods Enzymol       Date:  1997       Impact factor: 1.600

8.  Cellular physiology of STAT3: Where's the cytoplasmic monomer?

Authors:  M I Ndubuisi; G G Guo; V A Fried; J D Etlinger; P B Sehgal
Journal:  J Biol Chem       Date:  1999-09-03       Impact factor: 5.157

9.  Structure of an activated Dictyostelium STAT in its DNA-unbound form.

Authors:  Montserrat Soler-Lopez; Carlo Petosa; Masashi Fukuzawa; Raimond Ravelli; Jeffrey G Williams; Christoph W Müller
Journal:  Mol Cell       Date:  2004-03-26       Impact factor: 17.970

10.  N-domain-dependent nonphosphorylated STAT4 dimers required for cytokine-driven activation.

Authors:  Naruhisa Ota; Tom J Brett; Theresa L Murphy; Daved H Fremont; Kenneth M Murphy
Journal:  Nat Immunol       Date:  2004-01-04       Impact factor: 25.606
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  5 in total

1.  A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R.

Authors:  Alexis Kaushansky; Andrew Gordus; Bryan Chang; John Rush; Gavin MacBeath
Journal:  Mol Biosyst       Date:  2008-04-08

2.  Molecular mechanism and structural basis of gain-of-function of STAT1 caused by pathogenic R274Q mutation.

Authors:  Ryoji Fujiki; Atsushi Hijikata; Tsuyoshi Shirai; Satoshi Okada; Masao Kobayashi; Osamu Ohara
Journal:  J Biol Chem       Date:  2017-03-03       Impact factor: 5.157

3.  Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1.

Authors:  Adrian Mehlitz; Sebastian Banhart; André P Mäurer; Alexis Kaushansky; Andrew G Gordus; Julia Zielecki; Gavin Macbeath; Thomas F Meyer
Journal:  J Cell Biol       Date:  2010-07-12       Impact factor: 10.539

4.  Increasing the X-ray diffraction power of protein crystals by dehydration: the case of bovine serum albumin and a survey of literature data.

Authors:  Irene Russo Krauss; Filomena Sica; Carlo Andrea Mattia; Antonello Merlino
Journal:  Int J Mol Sci       Date:  2012-03-21       Impact factor: 6.208

Review 5.  STAT1 and pathogens, not a friendly relationship.

Authors:  Imen Najjar; Remi Fagard
Journal:  Biochimie       Date:  2010-02-13       Impact factor: 4.079
  5 in total

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