Literature DB >> 16510641

A randomized trial of home oxygen therapy from the emergency department for acute bronchiolitis.

Lalit Bajaj1, Carol G Turner, Joan Bothner.   

Abstract

OBJECTIVE: Hypoxia is a common reason for hospital admission in infants and children with acute bronchiolitis. No study has evaluated discharge from the emergency department (ED) on home oxygen. This study evaluated the feasibility and safety of ED discharge on home oxygen in the treatment of acute bronchiolitis.
METHODS: This was a prospective, randomized trial of infants and children with acute bronchiolitis and hypoxia (room-air saturations of < or =87%) aged 2 to 24 months presenting to an urban, academic, tertiary care children's hospital ED from December 1998 to April 2001. Subjects received inpatient admission or home oxygen after an 8-hour observation period in the ED. We measured the failure to meet discharge criteria during the observation period, return for hospital admission, and incidence of serious complications.
RESULTS: Ninety-two patients were enrolled. Fifty three (58%) were randomly assigned to home and 39 (42%) to inpatient admission. There were no differences between the groups in age, initial room-air saturation, and respiratory distress severity score. Of 53 patients, 37 (70%) randomly assigned to home oxygen completed the observation period and were discharged from the hospital. The remaining 16 patients were excluded from the study (6), resolved their oxygen requirement (5), or failed to meet the discharge criteria and were admitted (5). One discharged patient (2.7%) returned to the hospital and was admitted for a cyanotic spell at home after the 24-hour follow-up appointment. The patient had an uncomplicated hospital course with a length of stay of 45 hours. The remaining 36 patients (97%) were treated successfully as outpatients with home oxygen. Satisfaction with home oxygen was high from the caregiver and the primary care provider.
CONCLUSIONS: Discharge from the ED on home oxygen after a period of observation is an option for patients with acute bronchiolitis. Secondary to the low incidence of complications, the safety of this practice will require a larger study.

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Mesh:

Year:  2006        PMID: 16510641     DOI: 10.1542/peds.2005-1322

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  10 in total

1.  Has the hospital become the place not to be for infants with bronchiolitis?

Authors:  Kris De Boeck
Journal:  Eur J Pediatr       Date:  2012-10-09       Impact factor: 3.183

Review 2.  Bronchiolitis.

Authors:  Thomas Bourke; Michael Shields
Journal:  BMJ Clin Evid       Date:  2011-04-11

3.  Impact of home oxygen therapy on hospital stay for infants with acute bronchiolitis.

Authors:  Marie Gauthier; Melanie Vincent; Sylvain Morneau; Isabelle Chevalier
Journal:  Eur J Pediatr       Date:  2012-09-27       Impact factor: 3.183

4.  Varying patterns of home oxygen use in infants at 23-43 weeks' gestation discharged from United States neonatal intensive care units.

Authors:  Joanne M Lagatta; Reese H Clark; David C Brousseau; Raymond G Hoffmann; Alan R Spitzer
Journal:  J Pediatr       Date:  2013-06-12       Impact factor: 4.406

Review 5.  Recent evidence on the management of bronchiolitis.

Authors:  Alan R Schroeder; Jonathan M Mansbach
Journal:  Curr Opin Pediatr       Date:  2014-06       Impact factor: 2.856

6.  Nine Seasons of a Bronchiolitis Observation Unit and Home Oxygen Therapy Protocol.

Authors:  Timothy J D Ohlsen; Alexander M Knudson; E Kent Korgenski; David R Sandweiss; Michelle G Hofmann; Tiffany S Glasgow; Eric R Coon
Journal:  J Hosp Med       Date:  2021-05       Impact factor: 2.960

Review 7.  Recent advances in the management of acute bronchiolitis.

Authors:  Claudia Ravaglia; Venerino Poletti
Journal:  F1000Prime Rep       Date:  2014-11-04

8.  Marked variability observed in inpatient management of bronchiolitis in three Finnish hospitals.

Authors:  Varpu Elenius; Eija Bergroth; Petri Koponen; Sami Remes; Pedro A Piedra; Janice A Espinola; Matti Korppi; Carlos A Camargo; Tuomas Jartti
Journal:  Acta Paediatr       Date:  2017-06-16       Impact factor: 2.299

Review 9.  A systematic review of the reporting of Data Monitoring Committees' roles, interim analysis and early termination in pediatric clinical trials.

Authors:  Ricardo M Fernandes; Johanna H van der Lee; Martin Offringa
Journal:  BMC Pediatr       Date:  2009-12-13       Impact factor: 2.125

10.  Epidemiological assessment of Respiratory Syncytial Virus infection in hospitalized infants, during the season 2005-2006 in Palermo, Italy.

Authors:  Paola Di Carlo; Amelia Romano; Ludovico Salsa; Alessandra Gueli; Antonella Poma; Fortunata Fucà; Piera Dones; Mirella Collura; Diego Pampinella; Delia Motisi; Giovanni Corsello
Journal:  Ital J Pediatr       Date:  2009-05-02       Impact factor: 2.638

  10 in total

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