Literature DB >> 1651055

Analysis of local antibody production in the vitreous humor of patients with severe uveitis.

G S Baarsma1, L Luyendijk, A Kijlstra, J de Vries, E Peperkamp, D A Mertens, J C van Meurs.   

Abstract

We analyzed the local antibody production in vitreous humor samples collected during vitrectomy in patients with severe vision-threatening uveitis. In 24 patients, paired serum and undiluted vitreous humor samples were collected and tested for antibodies against Toxoplasma gondii, herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus, and Toxocara canis. Total IgG and the Goldmann-Witmer coefficient were determined. The initial diagnosis of ocular toxoplasmosis could be confirmed in six of the seven patients. The seventh patient showed a local antibody production against herpes simplex virus. One of the three patients with chronic panuveitis at initial diagnosis showed a local antibody production against T. gondii. These last two findings resulted in a change in medical treatment. Analysis of local antibody production in vitreous humor samples is a valuable diagnostic tool.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1651055     DOI： 10.1016/s0002-9394(14)76693-0

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN： 0002-9394            Impact factor:   5.258


  10 in total

1.  Necrotising retinopathies simulating acute retinal necrosis syndrome.

Authors:  B Balansard; B Bodaghi; N Cassoux; C Fardeau; S Romand; F Rozenberg; N A Rao; P Lehoang
Journal:  Br J Ophthalmol       Date:  2005-01       Impact factor: 4.638

2.  A comparative study of the polymerase chain reaction and local antibody production in acute retinal necrosis syndrome and cytomegalovirus retinitis.

Authors:  T Abe; K Tsuchida; M Tamai
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1996-07       Impact factor: 3.117

3.  Polymerase chain reaction analysis of aqueous humour samples in necrotising retinitis.

Authors:  T H C Tran; F Rozenberg; N Cassoux; N A Rao; P LeHoang; B Bodaghi
Journal:  Br J Ophthalmol       Date:  2003-01       Impact factor: 4.638

Review 4.  Analysis of ocular fluids for local antibody production in uveitis.

Authors:  J H de Boer; L Luyendijk; A Rothova; A Kijlstra
Journal:  Br J Ophthalmol       Date:  1995-06       Impact factor: 4.638

5.  Use of the polymerase chain reaction in the diagnosis of acquired ocular toxoplasmosis in an immunocompetent adult.

Authors:  R M Manners; S O'Connell; E C Guy; D H Joynson; C R Canning; D E Etchells
Journal:  Br J Ophthalmol       Date:  1994-07       Impact factor: 4.638

6.  Diagnostic assays in cytomegalovirus retinitis: detection of herpesvirus by simultaneous application of the polymerase chain reaction and local antibody analysis on ocular fluid.

Authors:  P Doornenbal; G Seerp Baarsma; W G Quint; A Kijlstra; P H Rothbarth; H G Niesters
Journal:  Br J Ophthalmol       Date:  1996-03       Impact factor: 4.638

7.  Early aqueous humor analysis in patients with human ocular toxoplasmosis.

Authors:  J G Garweg; P Jacquier; M Boehnke
Journal:  J Clin Microbiol       Date:  2000-03       Impact factor: 5.948

8.  Diagnostic anterior chamber paracentesis in uveitis: a safe procedure?

Authors:  A Van der Lelij; A Rothova
Journal:  Br J Ophthalmol       Date:  1997-11       Impact factor: 4.638

Review 9.  Infectious Uveitis in Horses and New Insights in Its Leptospiral Biofilm-Related Pathogenesis.

Authors:  Bettina Wollanke; Hartmut Gerhards; Kerstin Ackermann
Journal:  Microorganisms       Date:  2022-02-07

10.  Pre-Clinical In-Vitro Studies on Parameters Governing Immune Complex Formation.

Authors:  Marie Fichter; Gesa Richter; Alexander Bepperling; Paul Wassmann
Journal:  Pharmaceutics       Date:  2022-06-13       Impact factor: 6.525
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.