Literature DB >> 16510137

Treatment of asthma with antileukotrienes: first line or last resort therapy?

Sven-Erik Dahlén1.   

Abstract

Twenty five years after the structure elucidation of slow reacting substance of anaphylaxis, antileukotrienes are established as a new therapeutic modality in asthma. The chapter reviews the biochemistry and pharmacology of leukotrienes and antileukotrienes with particular focus on the different usage of antileukotrienes for treatment of asthma and rhinitis in Europe and the US. Further research needs and new areas for leukotriene involvement in respiratory diseases are also discussed.

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Year:  2006        PMID: 16510137     DOI: 10.1016/j.ejphar.2005.12.070

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  33 in total

Review 1.  [Aspirin-Intolerance-Syndrom : a common and interdisciplinary disease].

Authors:  C Umbreit; J C Virchow; C Thorn; K Hörmann; L Klimek; O Pfaar
Journal:  Internist (Berl)       Date:  2010-09       Impact factor: 0.743

Review 2.  Eicosanoid regulation of pulmonary innate immunity post-hematopoietic stem cell transplantation.

Authors:  Megan N Ballinger; Tracy R McMillan; Bethany B Moore
Journal:  Arch Immunol Ther Exp (Warsz)       Date:  2007 Jan-Feb       Impact factor: 4.291

3.  Improving protein crystal quality by selective removal of a Ca(2+)-dependent membrane-insertion loop.

Authors:  David B Neau; Nathaniel C Gilbert; Sue G Bartlett; Adam Dassey; Marcia E Newcomer
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2007-10-24

4.  Discovery of Highly Potent Dual CysLT1 and CysLT2 Antagonist.

Authors:  Satoshi Itadani; Shinya Takahashi; Masaki Ima; Tetsuya Sekiguchi; Manabu Fujita; Yoshisuke Nakayama; Jun Takeuchi
Journal:  ACS Med Chem Lett       Date:  2014-10-06       Impact factor: 4.345

Review 5.  Oxidative stress and cellular pathways of asthma and inflammation: Therapeutic strategies and pharmacological targets.

Authors:  Vikas Mishra; Jaspreet Banga; Patricia Silveyra
Journal:  Pharmacol Ther       Date:  2017-08-23       Impact factor: 12.310

Review 6.  Leukotrienes and airway inflammation.

Authors:  Katsuhide Okunishi; Marc Peters-Golden
Journal:  Biochim Biophys Acta       Date:  2011-02-23

7.  Novel quinolinone-pyrazoline hybrids: synthesis and evaluation of antioxidant and lipoxygenase inhibitory activity.

Authors:  Ioanna Kostopoulou; Antonia Diassakou; Eleni Kavetsou; Eftichia Kritsi; Panagiotis Zoumpoulakis; Eleni Pontiki; Dimitra Hadjipavlou-Litina; Anastasia Detsi
Journal:  Mol Divers       Date:  2020-02-17       Impact factor: 2.943

8.  5-Lipoxygenase: mechanisms of regulation.

Authors:  Olof Rådmark; Bengt Samuelsson
Journal:  J Lipid Res       Date:  2008-11-05       Impact factor: 5.922

9.  Specific mediator inhibition by the NO donors SNP and NCX 2057 in the peripheral lung: implications for allergen-induced bronchoconstriction.

Authors:  Anna-Karin Larsson; Magnus Bäck; Jon O Lundberg; Sven-Erik Dahlén
Journal:  Respir Res       Date:  2009-06-04

10.  Increased interleukin-10 production and Th2 skewing in the absence of 5-lipoxygenase.

Authors:  Daniel DiMeo; Jun Tian; Juan Zhang; Seiko Narushima; Daniel J Berg
Journal:  Immunology       Date:  2007-09-25       Impact factor: 7.397

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