BACKGROUND: Metastases to the liver is the leading cause of death in patients with colorectal cancer. METHODS: The authors review the data on diagnosis and management of this clinical problem, and they discuss management options that can be considered. RESULTS: Complete surgical resection of metastases from colorectal cancer that are localized to the liver results in 5-year survival rates ranging from 26% to 40%. CONCLUSIONS: By adding modalities such as targeted systemic therapy and other "local" treatments for liver metastases, further gains in survival are anticipated.
BACKGROUND:Metastases to the liver is the leading cause of death in patients with colorectal cancer. METHODS: The authors review the data on diagnosis and management of this clinical problem, and they discuss management options that can be considered. RESULTS: Complete surgical resection of metastases from colorectal cancer that are localized to the liver results in 5-year survival rates ranging from 26% to 40%. CONCLUSIONS: By adding modalities such as targeted systemic therapy and other "local" treatments for liver metastases, further gains in survival are anticipated.
Authors: Nikolaos Vassos; Tilman Rau; Susanne Merkel; Fabian Feiersinger; Carol I Geppert; Michael Stürzl; Werner Hohenberger; Roland S Croner Journal: Int J Clin Exp Pathol Date: 2013-12-15
Authors: Paul G Toomey; Nasreen A Vohra; Tomar Ghansah; Amod A Sarnaik; Shari A Pilon-Thomas Journal: Cancer Control Date: 2013-01 Impact factor: 3.302
Authors: Dawid Storman; Mateusz J Swierz; Robert P Riemsma; Robert Wolff; Jerzy W Mitus; Michal Pedziwiatr; Jos Kleijnen; Malgorzata M Bala Journal: Cochrane Database Syst Rev Date: 2021-01-28
Authors: Eleanor I Ager; Shu Wen Wen; Joyna Chan; Way W Chong; Jaclyn H Neo; Christopher Christophi Journal: BMC Cancer Date: 2011-06-26 Impact factor: 4.430