Literature DB >> 1650662

Detection of herpes simplex virus DNA sequences in corneal transplant recipients by polymerase chain reaction assays.

E M Cantin1, J Chen, J McNeill, D E Willey, H Openshaw.   

Abstract

Polymerase chain reaction (PCR) assays were used to amplify herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) sequences in DNA extracted from formalin-fixed, paraffin embedded corneas of patients undergoing corneal transplantation. PCR reamplification with an internal (nested) set of primers was required for detection in 10 of the 12 positive corneas indicating very low abundance of viral sequences. Three of the positive corneal samples were from failed corneal grafts. Overall, TK sequences were detected in 8 of 11 corneas from subjects with a past history of herpes keratitis and in 4 of 11 corneas from subjects with no past history of herpetic eye disease.

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Year:  1991        PMID： 1650662     DOI： 10.3109/02713689109020353

Source DB:  PubMed          Journal:  Curr Eye Res        ISSN： 0271-3683            Impact factor:   2.424


  18 in total

1.  Human herpesviruses in the cornea.

Authors:  S B Kaye; K Baker; R Bonshek; H Maseruka; E Grinfeld; A Tullo; D L Easty; C A Hart
Journal:  Br J Ophthalmol       Date:  2000-06       Impact factor: 4.638

Review 2.  Herpes simplex virus in the eye.

Authors:  S D Cook
Journal:  Br J Ophthalmol       Date:  1992-06       Impact factor: 4.638

3.  Epidemiology and molecular analysis of herpes simplex keratitis requiring primary penetrating keratoplasty.

Authors:  B C Branco; P A Gaudio; T P Margolis
Journal:  Br J Ophthalmol       Date:  2004-10       Impact factor: 4.638

4.  Novel biotinylated lipid prodrugs of acyclovir for the treatment of herpetic keratitis (HK): transporter recognition, tissue stability and antiviral activity.

Authors:  Aswani Dutt Vadlapudi; Ramya Krishna Vadlapatla; Ravinder Earla; Suman Sirimulla; Jake Brain Bailey; Dhananjay Pal; Ashim K Mitra
Journal:  Pharm Res       Date:  2013-05-09       Impact factor: 4.200

5.  Specific antibody production in herpes keratitis: intraocular inflammation and corneal neovascularisation as predicting factors.

Authors:  Pierre-Yves Robert; Anja Liekfeld; Sylvia Metzner; Sylvie Ranger-Rogez; Jean-Paul Adenis; François Denis; Christian Hartmann; Uwe Pleyer
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-07-26       Impact factor: 3.117

6.  Slow viral replication of HSV-1 is responsible for early recurrence of herpetic keratitis after corneal grafting.

Authors:  J Garweg; M Böhnke
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1996-08       Impact factor: 3.117

7.  Detection of herpes simplex virus after penetrating keratoplasty by polymerase chain reaction: correlation of clinical and laboratory findings.

Authors:  H Mietz; P Cassinotti; G Siegl; B Kirchhof; G K Krieglstein
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1995-11       Impact factor: 3.117

8.  2-[4,5-Difluoro-2-(2-fluorobenzoylamino)-benzoylamino]benzoic acid, an antiviral compound with activity against acyclovir-resistant isolates of herpes simplex virus types 1 and 2.

Authors:  Mårten Strand; Koushikul Islam; Karin Edlund; Christopher T Oberg; Annika Allard; Tomas Bergström; Ya-Fang Mei; Mikael Elofsson; Göran Wadell
Journal:  Antimicrob Agents Chemother       Date:  2012-08-20       Impact factor: 5.191

9.  The relationship of graft survival and herpes simplex virus latency in recipient corneal buttons.

Authors:  Orhan Aydemir; Peykan Türkçüoğlu; Yasemin Bulut; Ahmet Kalkan
Journal:  Clin Ophthalmol       Date:  2007-06

10.  Detection of active and latent feline herpesvirus 1 infections using the polymerase chain reaction.

Authors:  G H Reubel; R A Ramos; M A Hickman; E Rimstad; D E Hoffmann; N C Pedersen
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574
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