Literature DB >> 16504809

Options for medical treatment of myomas.

Beth W Rackow1, Aydin Arici.   

Abstract

It is evident that complex biochemical interactions are involved in the regulation of myoma growth, and ovarian steroid hormones have significant influence on this process. Current myoma therapies manipulate the hormonal environment to achieve myoma regression and control of bleeding. Although several of these therapies achieve some level of success, further studies are necessary to evaluate the current and long-term effects of these therapies. In clinical medicine each patient must be evaluated thoroughly, and the decision for medical therapy or surgery--and for which medical therapy--needs to be individualized. If one medical therapy does not work, several other effective therapies are available.

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Year:  2006        PMID: 16504809     DOI: 10.1016/j.ogc.2005.12.014

Source DB:  PubMed          Journal:  Obstet Gynecol Clin North Am        ISSN: 0889-8545            Impact factor:   2.844


  6 in total

1.  Predominant suppression of follicle-stimulating hormone β-immunoreactivity after long-term treatment of intact and castrate adult male rats with the gonadotrophin-releasing hormone agonist deslorelin.

Authors:  A W Smith; C S Asa; B S Edwards; W J Murdoch; D C Skinner
Journal:  J Neuroendocrinol       Date:  2012-05       Impact factor: 3.627

2.  Obstructive uropathy secondary to uterine leiomyoma in a chimpanzee (Pan troglodytes).

Authors:  Patrick W Hanley; Kirstin F Barnhart; William C Satterfield; Mark J McArthur; Stephanie J Buchl; Wallace B Baze
Journal:  Comp Med       Date:  2012-12       Impact factor: 0.982

3.  A high concentration of genistein down-regulates activin A, Smad3 and other TGF-β pathway genes in human uterine leiomyoma cells.

Authors:  Xudong Di; Danica M K Andrews; Charles J Tucker; Linda Yu; Alicia B Moore; Xiaolin Zheng; Lysandra Castro; Tonia Hermon; Hang Xiao; Darlene Dixon
Journal:  Exp Mol Med       Date:  2012-04-30       Impact factor: 8.718

4.  Effect of Vitamin D3 Supplementation on Symptomatic Uterine Leiomyoma in Women with Hypovitaminosis D.

Authors:  Amita Suneja; Fahmina Faridi; Shuchi Bhatt; Kiran Guleria; Mohit Mehndiratta; Richa Sharma
Journal:  J Midlife Health       Date:  2021-04-17

5.  Effect of a selective progesterone receptor modulator on induction of apoptosis in uterine fibroids in vivo.

Authors:  Petr Horak; Michal Mara; Pavel Dundr; Kristyna Kubinova; David Kuzel; Robert Hudecek; Roman Chmel
Journal:  Int J Endocrinol       Date:  2012-07-16       Impact factor: 3.257

6.  Comparison of the inhibitory effect of gonadotropin releasing hormone (GnRH) agonist, selective estrogen receptor modulator (SERM), antiprogesterone on myoma cell proliferation in vitro.

Authors:  Youn-Jee Chung; Boah Chae; Se-Hyun Kwak; Jae-Yen Song; Ah-Won Lee; Hyun-Hee Jo; Young-Ok Lew; Jang-Heub Kim; Mee-Ran Kim
Journal:  Int J Med Sci       Date:  2014-01-28       Impact factor: 3.738

  6 in total

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