OBJECTIVE: The aim of this study was to test three techniques used simultaneously to increase lesion size. BACKGROUND DATA: Laser-induced thermotherapy (LITT) is a method of local tumor ablation, which may prolong survival in patients with unresectable liver metastases. The main limitation has been the production of lesions with sufficient tumor-free margin. METHODS: LITT treatment was performed with water-cooled, multiple fiber application and hepatic blood flow occlusion in six patients with unresectable intrahepatic metastases. Response was measured by computed tomography scan. RESULTS: In all patients, tumors were effectively ablated. In two patients with colorectal metastases, lesions up to 8.6 cm could be created. CONCLUSION: The use of watercooled multiple fiber application and hepatic inflow occlusion makes LITT an effective ablative method, expanding the treatment options for patients with large intrahepatic masses.
OBJECTIVE: The aim of this study was to test three techniques used simultaneously to increase lesion size. BACKGROUND DATA: Laser-induced thermotherapy (LITT) is a method of local tumor ablation, which may prolong survival in patients with unresectable liver metastases. The main limitation has been the production of lesions with sufficient tumor-free margin. METHODS:LITT treatment was performed with water-cooled, multiple fiber application and hepatic blood flow occlusion in six patients with unresectable intrahepatic metastases. Response was measured by computed tomography scan. RESULTS: In all patients, tumors were effectively ablated. In two patients with colorectal metastases, lesions up to 8.6 cm could be created. CONCLUSION: The use of watercooled multiple fiber application and hepatic inflow occlusion makes LITT an effective ablative method, expanding the treatment options for patients with large intrahepatic masses.
Authors: Paola Saccomandi; Emiliano Schena; Francesco Giurazza; Riccardo Del Vescovo; Michele A Caponero; Luca Mortato; Francesco Panzera; Roberto L Cazzato; Francesco R Grasso; Francesco M Di Matteo; Sergio Silvestri; Bruno B Zobel Journal: Lasers Med Sci Date: 2013-06-19 Impact factor: 3.161
Authors: Junichi Tokuda; Laurent Chauvin; Brian Ninni; Takahisa Kato; Franklin King; Kemal Tuncali; Nobuhiko Hata Journal: Phys Med Biol Date: 2018-04-13 Impact factor: 3.609
Authors: Pretesh R Patel; Alfred Luk; Amirk Durrani; Sergio Dromi; Julian Cuesta; Mary Angstadt; Matthew R Dreher; Bradford J Wood; Victor Frenkel Journal: Int J Hyperthermia Date: 2008-11 Impact factor: 3.914
Authors: Liesbeth M Veenendaal; Inne H M Borel Rinkes; Cornelis J M Lips; Richard van Hillegersberg Journal: World J Surg Oncol Date: 2006-06-26 Impact factor: 2.754