Literature DB >> 16502342

Polyinosinic-polycytidylic acid induces the expression of GRO-alpha in BEAS-2B cells.

Koji Yamashita1, Tadaatsu Imaizumi, Kageaki Taima, Takashi Fujita, Akira Ishikawa, Hidemi Yoshida, Chikara Oyama, Kei Satoh.   

Abstract

Growth-related oncogene protein-alpha (GRO-alpha)/CXCLl is a chemokine that activates neutrophils and plays an important role in inflammatory reactions. Polyinosinic-polycytidylic acid (poly IC) is a synthetic double-stranded RNA (dsRNA), which is a ligand for Toll-like receptor-3. Poly IC mimics viral infection when applied to cells and induces inflammatory and immune responses. In the present study, we found the induction of GRO-alpha in BEAS-2B bronchial epithelial cells treated with poly IC. Pretreatment of cells with 2-aminopurine, an inhibitor for dsRNA-dependent protein kinase (PKR), inhibited the expression of GRO-alpha-induced by poly IC. Overexpression of interferon-regulatory factor-3 (IRF-3) or retinoic-acid inducible gene-I (RIG-I) enhanced the induction of GRO-alpha by poly IC. PKR, IRF-3, and RIG-I may be involved in the poly IC-induced expression of GRO-alpha in BEAS-2B cells. Airway viral infection may elicit GRO-alpha expression in the bronchial epithelium, which may be implicated in inflammatory and immune reactions.

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Year:  2005        PMID： 16502342     DOI： 10.1007/s10753-006-8964-4

Source DB:  PubMed          Journal:  Inflammation        ISSN： 0360-3997            Impact factor:   4.092


  23 in total

1.  Effect of MG132, a proteasome inhibitor, on the expression of growth related oncogene protein-alpha in human umbilical vein endothelial cells.

Authors:  Takeo Shibata; Tadaatsu Imaizumi; Tomoh Matsumiya; Wakako Tamo; Masaharu Hatakeyama; Hidemi Yoshida; Hirohumi Munakata; Ikuo Fukuda; Kei Satoh
Journal:  Cytokine       Date:  2003-11-07       Impact factor: 3.861

Review 2.  Control of IRF-3 activation by phosphorylation.

Authors:  Mitsutoshi Yoneyama; Wakako Suhara; Takashi Fujita
Journal:  J Interferon Cytokine Res       Date:  2002-01       Impact factor: 2.607

3.  Production of growth related oncogene protein-alpha in human umbilical vein endothelial cells stimulated with soluble interleukin-6 receptor-alpha: role of signal transducers, janus kinase 2 and mitogen-activated kinase kinase.

Authors:  Tomoh Matsumiya; Tadaatsu Imaizumi; Hiroyuki Itaya; Takeo Shibata; Hidemi Yoshida; Hirotaka Sakaki; Hiroto Kimura; Kei Satoh
Journal:  Life Sci       Date:  2002-05-17       Impact factor: 5.037

4.  Retinoic acid-inducible gene-I is induced in endothelial cells by LPS and regulates expression of COX-2.

Authors:  Tadaatsu Imaizumi; Satoko Aratani; Toshihiro Nakajima; Mary Carlson; Tomoh Matsumiya; Kunikazu Tanji; Keizou Ookawa; Hidemi Yoshida; Shigeki Tsuchida; Thomas M McIntyre; Stephen M Prescott; Guy A Zimmerman; Kei Satoh
Journal:  Biochem Biophys Res Commun       Date:  2002-03-22       Impact factor: 3.575

5.  Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus.

Authors:  Loïc Guillot; Ronan Le Goffic; Sarah Bloch; Nicolas Escriou; Shizuo Akira; Michel Chignard; Mustapha Si-Tahar
Journal:  J Biol Chem       Date:  2004-12-03       Impact factor: 5.157

6.  Interferon-gamma induces retinoic acid-inducible gene-I in endothelial cells.

Authors:  T Imaizumi; M Hatakeyama; K Yamashita; H Yoshida; A Ishikawa; K Taima; K Satoh; F Mori; K Wakabayashi
Journal:  Endothelium       Date:  2004 May-Aug

7.  Neoplastic transformation of a human bronchial epithelial cell line by a recombinant retrovirus encoding viral Harvey ras.

Authors:  P Amstad; R R Reddel; A Pfeifer; L Malan-Shibley; G E Mark; C C Harris
Journal:  Mol Carcinog       Date:  1988       Impact factor: 4.784

8.  Tumour necrosis factor-alpha induced CD70 and interleukin-7R mRNA expression in BEAS-2B cells.

Authors:  K Wolf; C Schulz; G A J Riegger; M Pfeifer
Journal:  Eur Respir J       Date:  2002-08       Impact factor: 16.671

9.  Expression of retinoic acid-inducible gene-I in vascular smooth muscle cells stimulated with interferon-gamma.

Authors:  Tadaatsu Imaizumi; Norito Yagihashi; Masaharu Hatakeyama; Koji Yamashita; Akira Ishikawa; Kageaki Taima; Hidemi Yoshida; Ituro Inoue; Takashi Fujita; Soroku Yagihashi; Kei Satoh
Journal:  Life Sci       Date:  2004-07-23       Impact factor: 5.037

10.  Lipopolysaccharide-stimulated human monocytes secrete, apart from neutrophil-activating peptide 1/interleukin 8, a second neutrophil-activating protein. NH2-terminal amino acid sequence identity with melanoma growth stimulatory activity.

Authors:  J M Schröder; N L Persoon; E Christophers
Journal:  J Exp Med       Date:  1990-04-01       Impact factor: 14.307
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  3 in total

1.  Prostaglandin I(2) analogues enhance growth-related oncogene-alpha expression in human monocyte-derived dendritic cells.

Authors:  Chang-Hung Kuo; Ren-Long Jan; Yu-Te Chu; Wei-Li Wang; Ming-Yii Huang; Ching-Hua Huang; Tai-Heng Chen; Chih-Hsing Hung
Journal:  Inflammation       Date:  2010-10       Impact factor: 4.092

2.  Regulation of TLR2 expression and function in human airway epithelial cells.

Authors:  Tamene Melkamu; Diane Squillace; Hirohito Kita; Scott M O'Grady
Journal:  J Membr Biol       Date:  2009-06-10       Impact factor: 1.843

3.  Short-hairpin RNAs delivered by lentiviral vector transduction trigger RIG-I-mediated IFN activation.

Authors:  Rachael Kenworthy; Diana Lambert; Feng Yang; Nan Wang; Zihong Chen; Haizhen Zhu; Fanxiu Zhu; Chen Liu; Kui Li; Hengli Tang
Journal:  Nucleic Acids Res       Date:  2009-09-03       Impact factor: 16.971
  3 in total

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