Literature DB >> 1650188

Raf-1 is a potential substrate for mitogen-activated protein kinase in vivo.

N G Anderson1, P Li, L A Marsden, N Williams, T M Roberts, T W Sturgill.   

Abstract

MAP (mitogen-activated protein) kinase is shown to phosphorylate baculovirally expressed Raf-1 in vitro, generating one major tryptic phosphopeptide which co-migrated with a peptide from Raf-1 32P-labelled in situ. This peptide also undergoes an insulin-dependent increase in labelling. Thus the serine/threonine kinase Raf-1 may be a substrate for MAP kinase in vivo.

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Year:  1991        PMID: 1650188      PMCID: PMC1151274          DOI: 10.1042/bj2770573

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  21 in total

Review 1.  Protein kinase cascades in meiotic and mitotic cell cycle control.

Authors:  S L Pelech; J S Sanghera; M Daya-Makin
Journal:  Biochem Cell Biol       Date:  1990-12       Impact factor: 3.626

Review 2.  Growth factor receptor tyrosine kinases.

Authors:  Y Yarden; A Ullrich
Journal:  Annu Rev Biochem       Date:  1988       Impact factor: 23.643

3.  Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor.

Authors:  D K Morrison; D R Kaplan; J A Escobedo; U R Rapp; T M Roberts; L T Williams
Journal:  Cell       Date:  1989-08-25       Impact factor: 41.582

4.  raf family serine/threonine protein kinases in mitogen signal transduction.

Authors:  U R Rapp; G Heidecker; M Huleihel; J L Cleveland; W C Choi; T Pawson; J N Ihle; W B Anderson
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1988

5.  Transforming gene product of Rous sarcoma virus phosphorylates tyrosine.

Authors:  T Hunter; B M Sefton
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

6.  A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis.

Authors:  D A McClain; H Maegawa; J Lee; T J Dull; A Ulrich; J M Olefsky
Journal:  J Biol Chem       Date:  1987-10-25       Impact factor: 5.157

7.  Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity.

Authors:  D K Morrison; D R Kaplan; U Rapp; T M Roberts
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

8.  T cell antigen receptor engagement stimulates c-raf phosphorylation and induces c-raf-associated kinase activity via a protein kinase C-dependent pathway.

Authors:  J N Siegel; R D Klausner; U R Rapp; L E Samelson
Journal:  J Biol Chem       Date:  1990-10-25       Impact factor: 5.157

9.  Identification by mass spectrometry of threonine 97 in bovine myelin basic protein as a specific phosphorylation site for mitogen-activated protein kinase.

Authors:  A K Erickson; D M Payne; P A Martino; A J Rossomando; J Shabanowitz; M J Weber; D F Hunt; T W Sturgill
Journal:  J Biol Chem       Date:  1990-11-15       Impact factor: 5.157

10.  Epidermal growth factor (EGF) receptor T669 peptide kinase from 3T3-L1 cells is an EGF-stimulated "MAP" kinase.

Authors:  K Takishima; I Griswold-Prenner; T Ingebritsen; M R Rosner
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-15       Impact factor: 11.205

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  38 in total

1.  Selective activation of p42 mitogen-activated protein (MAP) kinase in murine B lymphoma cell lines by membrane immunoglobulin cross-linking. Evidence for protein kinase C-independent and -dependent mechanisms of activation.

Authors:  M R Gold; J S Sanghera; J Stewart; S L Pelech
Journal:  Biochem J       Date:  1992-10-01       Impact factor: 3.857

Review 2.  Molecular signal integration. Interplay between serine, threonine, and tyrosine phosphorylation.

Authors:  J Posada; J A Cooper
Journal:  Mol Biol Cell       Date:  1992-06       Impact factor: 4.138

Review 3.  Extracellular signal-regulated kinases: ERKs in progress.

Authors:  M H Cobb; T G Boulton; D J Robbins
Journal:  Cell Regul       Date:  1991-12

4.  Basal extracellular signal-regulated kinase activity modulates cell-cell and cell-matrix interactions.

Authors:  Q Lu; M Paredes; J Zhang; K S Kosik
Journal:  Mol Cell Biol       Date:  1998-06       Impact factor: 4.272

5.  The pool of map kinase associated with microtubules is small but constitutively active.

Authors:  M Morishima-Kawashima; K S Kosik
Journal:  Mol Biol Cell       Date:  1996-06       Impact factor: 4.138

6.  Insulin receptor serine kinase activation by casein kinase 2 and a membrane tyrosine kinase.

Authors:  T J Singh
Journal:  Mol Cell Biochem       Date:  1993-04-21       Impact factor: 3.396

7.  Direct stimulation by tyrosine phosphorylation of microtubule-associated protein (MAP) kinase activity by granulocyte-macrophage colony-stimulating factor in human neutrophils.

Authors:  J Gomez-Cambronero; J M Colasanto; C K Huang; R I Sha'afi
Journal:  Biochem J       Date:  1993-04-01       Impact factor: 3.857

8.  Cloning and characterization of p97MAPK, a novel human homolog of rat ERK-3.

Authors:  A X Zhu; Y Zhao; D E Moller; J S Flier
Journal:  Mol Cell Biol       Date:  1994-12       Impact factor: 4.272

9.  Protein-tyrosine-phosphatase 2C is phosphorylated and inhibited by 44-kDa mitogen-activated protein kinase.

Authors:  P Peraldi; Z Zhao; C Filloux; E H Fischer; E Van Obberghen
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-24       Impact factor: 11.205

10.  Endothelin rapidly stimulates mitogen-activated protein kinase activity in rat mesangial cells.

Authors:  Y Wang; M S Simonson; J Pouysségur; M J Dunn
Journal:  Biochem J       Date:  1992-10-15       Impact factor: 3.857

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