Literature DB >> 16500788

A case of Ascaris suum visceral larva migrans diagnosed by using A. suum larval excretory-secretory (ES) antigen.

Fukumi Nakamura-Uchiyama1, Yoshifumi Tokunaga, Asahi Suzuki, Nobuaki Akao, Kenji Hiromatsu, Shigemi Hitomi, Yukifumi Nawa.   

Abstract

A 42-y-old female presented with common cold-like symptoms. Laboratory data showed mild liver dysfunction together with peripheral blood eosinophilia. She was suspected of having a helminthic infection, however parasite eggs or larvae were not detected by repeated stool examinations. Eventually she transpired to have a high IgG antibody titer against excretory-secretary (ES) antigen of Ascaris suum larvae, but not of Toxocara canis larvae, suggesting that she had been suffering from visceral larva migrans (VLM) caused by A. suum. Her sickness improved without any treatment. Current results clearly highlight the usefulness of ES antigens derived from larvae of A. suum for the fine discrimination of VLM caused by A. suum and by T. canis. Application of A. suum derived ES antigens as a diagnostic tool may reveal the distinctive clinical features of VLM caused by A. suum.

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Year:  2006        PMID: 16500788     DOI: 10.1080/00365540500348952

Source DB:  PubMed          Journal:  Scand J Infect Dis        ISSN: 0036-5548


  6 in total

1.  Immunoblot for the detection of Ascaris suum-specific antibodies in patients with visceral larva migrans (VLM) syndrome.

Authors:  Renate Schneider; Andreas Obwaller; Herbert Auer
Journal:  Parasitol Res       Date:  2014-11-01       Impact factor: 2.289

Review 2.  Larva migrans in India: veterinary and public health perspectives.

Authors:  Rajnish Sharma; B B Singh; J P S Gill
Journal:  J Parasit Dis       Date:  2013-12-03

3.  Oral immunogenicity and protective efficacy in mice of transgenic rice plants producing a vaccine candidate antigen (As16) of Ascaris suum fused with cholera toxin B subunit.

Authors:  Yasunobu Matsumoto; Seiko Suzuki; Tomoko Nozoye; Takashi Yamakawa; Yasuhiro Takashima; Takeshi Arakawa; Naotoshi Tsuji; Fumio Takaiwa; Yoshihiro Hayashi
Journal:  Transgenic Res       Date:  2008-09-02       Impact factor: 2.788

4.  Optimal ELISA antigen for the diagnosis of Ascaris suum infection in humans.

Authors:  Ayako Yoshida; Taisei Kikuchi; Shiori Nakagaki; Haruhiko Maruyama
Journal:  Parasitol Res       Date:  2016-09-08       Impact factor: 2.289

5.  Prevalence of antibodies against Ascaris suum and its association with allergic manifestations in 4-year-old children in The Netherlands: the PIAMA birth cohort study.

Authors:  E Pinelli; S M Willers; D Hoek; H A Smit; L M Kortbeek; M Hoekstra; J de Jongste; F van Knapen; D Postma; M Kerkhof; R Aalberse; J W B van der Giessen; B Brunekreef
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2009-07-31       Impact factor: 3.267

6.  Pediatric neurocysticercosis: usefulness of antibody response in cysticidal treatment follow-up.

Authors:  Venkata Subba Rao Atluri; Venkateswara Reddy Gogulamudi; Pratibha Singhi; Niranjan Khandelwal; Lakshmana Swamy Parasa; Nancy Malla
Journal:  Biomed Res Int       Date:  2014-08-06       Impact factor: 3.411

  6 in total

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