Literature DB >> 16500368

Estimation of human sperm gene-specific deoxyribonucleic acid damage by real-time polymerase chain reaction analysis.

Maria San Gabriel1, Xiaoyang Zhang, Armand Zini.   

Abstract

It has been reported that spermatozoa of infertile men have poorer DNA integrity than that of fertile men. Using analyses based on real-time polymerase chain reaction, we have estimated the relative gene-specific DNA damage in human spermatozoa and have observed that the spermatozoa of infertile men possess measurably more DNA damage than that of fertile men.

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Year:  2006        PMID: 16500368     DOI: 10.1016/j.fertnstert.2005.11.027

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  2 in total

1.  DNA damage reduces Taq DNA polymerase fidelity and PCR amplification efficiency.

Authors:  Jan A Sikorsky; Donald A Primerano; Terry W Fenger; James Denvir
Journal:  Biochem Biophys Res Commun       Date:  2007-02-07       Impact factor: 3.575

2.  Sub-fertile sperm cells exemplify telomere dysfunction.

Authors:  Tal Biron-Shental; Amir Wiser; Anat Hershko-Klement; Ofer Markovitch; Aliza Amiel; Arie Berkovitch
Journal:  J Assist Reprod Genet       Date:  2017-09-13       Impact factor: 3.412

  2 in total

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