OBJECTIVE: To study the chemical constituents of the root of Rhaponticum uniflorum. METHOD: Separation and purification were performed on silica gel and Sephadex LH-20 column chromatography. Their structure were elucidated on the basis of physicochemical and spectral analysis. RESULT: Five triterpenoid compounds were isolated and identified as ursolic acid (1), 3-oxo-19alpha-hydroxyurs-12-en-28-oic acid (2), pomolic acid (3), arjunic acid (4) and tormentic acid (5), respectively. CONCLUSION: Compounds 1 approximately 5 were isolated from the genus Rhaponticum for the first time.
OBJECTIVE: To study the chemical constituents of the root of Rhaponticum uniflorum. METHOD: Separation and purification were performed on silica gel and Sephadex LH-20 column chromatography. Their structure were elucidated on the basis of physicochemical and spectral analysis. RESULT: Five triterpenoid compounds were isolated and identified as ursolic acid (1), 3-oxo-19alpha-hydroxyurs-12-en-28-oic acid (2), pomolic acid (3), arjunic acid (4) and tormentic acid (5), respectively. CONCLUSION: Compounds 1 approximately 5 were isolated from the genus Rhaponticum for the first time.