Literature DB >> 1649895

Induction of chromosome abnormalities in mouse and human epidermal keratinocytes by the human papillomavirus type 16 E7 oncogene.

T Hashida1, S Yasumoto.   

Abstract

Cytogenetic abnormalities associated with human papillomavirus (HPV) type 16 were studied using primary human and mouse epidermal keratinocytes. The E7 transforming gene of HPV-16 was found to induce chromosome duplication in epidermal keratinocytes; little or no detectable chromosome disorganization was associated with the function of the E6 gene. These results suggest that the E7 gene-linked cytogenetic effect reflects HPV-16-associated pathogenicity in the early phase of transformation.

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Year:  1991        PMID: 1649895     DOI: 10.1099/0022-1317-72-7-1569

Source DB:  PubMed          Journal:  J Gen Virol        ISSN: 0022-1317            Impact factor:   3.891


  15 in total

Review 1.  Genomic instability and cancer: lessons learned from human papillomaviruses.

Authors:  Nina Korzeniewski; Nicole Spardy; Anette Duensing; Stefan Duensing
Journal:  Cancer Lett       Date:  2010-11-13       Impact factor: 8.679

2.  Clinical significance of hWAPL polymorphisms in the risk of cervical carcinogenesis.

Authors:  Osamu Nunobiki; Daisuke Sano; Sakae Hata; Toshitada Ogasawara; Masatsugu Ueda
Journal:  Hum Cell       Date:  2018-01-23       Impact factor: 4.174

Review 3.  Manipulation of cellular DNA damage repair machinery facilitates propagation of human papillomaviruses.

Authors:  Nicholas A Wallace; Denise A Galloway
Journal:  Semin Cancer Biol       Date:  2014-01-08       Impact factor: 15.707

4.  Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes.

Authors:  S Duensing; A Duensing; E R Flores; A Do; P F Lambert; K Münger
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

5.  The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle.

Authors:  S Duensing; L Y Lee; A Duensing; J Basile; S Piboonniyom; S Gonzalez; C P Crum; K Munger
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-29       Impact factor: 11.205

6.  Robertsonian translocation as a result of telomere shortening during replicative senescence and immortalization of bovine oviduct epithelial cells.

Authors:  Ken Murata; Kei Hanzawa; Fumio Kasai; Masakatsu Takeuchi; Tomoko Echigoya; Shigeru Yasumoto
Journal:  In Vitro Cell Dev Biol Anim       Date:  2007-09-09       Impact factor: 2.416

Review 7.  Role of human immunodeficiency virus infection in the pathogenesis of human papillomavirus-associated cervical neoplasia.

Authors:  L Braun
Journal:  Am J Pathol       Date:  1994-02       Impact factor: 4.307

Review 8.  Pathogenesis of human papillomaviruses in differentiating epithelia.

Authors:  Michelle S Longworth; Laimonis A Laimins
Journal:  Microbiol Mol Biol Rev       Date:  2004-06       Impact factor: 11.056

Review 9.  Molecular mechanisms of human papillomavirus-induced carcinogenesis.

Authors:  Michaël Lehoux; Claudia M D'Abramo; Jacques Archambault
Journal:  Public Health Genomics       Date:  2009-08-11       Impact factor: 2.000

10.  Hepatitis C virus causes uncoupling of mitotic checkpoint and chromosomal polyploidy through the Rb pathway.

Authors:  Keigo Machida; Jian-Chang Liu; George McNamara; Alexandra Levine; Lewei Duan; Michael M C Lai
Journal:  J Virol       Date:  2009-09-30       Impact factor: 5.103

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